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PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation.
Farabaugh KT, Krokowski D, Guan BJ, Gao Z, Gao XH, Wu J, Jobava R, Ray G, de Jesus TJ, Bianchi MG, Chukwurah E, Bussolati O, Kilberg M, Buchner DA, Sen GC, Cotton C, McDonald C, Longworth M, Ramakrishnan P, Hatzoglou M. Farabaugh KT, et al. Among authors: longworth m. Elife. 2020 Mar 16;9:e52241. doi: 10.7554/eLife.52241. Elife. 2020. PMID: 32175843 Free PMC article.
Chromosome-associated protein D3 promotes bacterial clearance in human intestinal epithelial cells by repressing expression of amino acid transporters.
Schuster AT, Homer CR, Kemp JR, Nickerson KP, Deutschman E, Kim Y, West G, Sadler T, Stylianou E, Krokowski D, Hatzoglou M, de la Motte C, Rubin BP, Fiocchi C, McDonald C, Longworth MS. Schuster AT, et al. Among authors: longworth ms. Gastroenterology. 2015 Jun;148(7):1405-1416.e3. doi: 10.1053/j.gastro.2015.02.013. Epub 2015 Feb 18. Gastroenterology. 2015. PMID: 25701737 Free PMC article.
Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress.
Farabaugh KT, Majumder M, Guan BJ, Jobava R, Wu J, Krokowski D, Gao XH, Schuster A, Longworth M, Chan ED, Bianchi M, Dey M, Koromilas AE, Ramakrishnan P, Hatzoglou M. Farabaugh KT, et al. Among authors: longworth m. Mol Cell Biol. 2017 Feb 1;37(4):e00521-16. doi: 10.1128/MCB.00521-16. Print 2017 Feb 15. Mol Cell Biol. 2017. PMID: 27920257 Free PMC article.
Retrotransposons in embryogenesis and neurodevelopment.
Talley MJ, Longworth MS. Talley MJ, et al. Among authors: longworth ms. Biochem Soc Trans. 2024 May 8:BST20230757. doi: 10.1042/BST20230757. Online ahead of print. Biochem Soc Trans. 2024. PMID: 38716891
64 results