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Fasting and fasting-mimicking treatment activate SIRT1/LXRα and alleviate diabetes-induced systemic and microvascular dysfunction.
Hammer SS, Vieira CP, McFarland D, Sandler M, Levitsky Y, Dorweiler TF, Lydic TA, Asare-Bediako B, Adu-Agyeiwaah Y, Sielski MS, Dupont M, Longhini AL, Li Calzi S, Chakraborty D, Seigel GM, Proshlyakov DA, Grant MB, Busik JV. Hammer SS, et al. Among authors: longhini al. Diabetologia. 2021 Jul;64(7):1674-1689. doi: 10.1007/s00125-021-05431-5. Epub 2021 Mar 26. Diabetologia. 2021. PMID: 33770194 Free PMC article.
Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes.
Vieira CP, Fortmann SD, Hossain M, Longhini AL, Hammer SS, Asare-Bediako B, Crossman DK, Sielski MS, Adu-Agyeiwaah Y, Dupont M, Floyd JL, Li Calzi S, Lydic T, Welner RS, Blanchard GJ, Busik JV, Grant MB. Vieira CP, et al. Among authors: longhini al. JCI Insight. 2020 Jul 9;5(13):e137230. doi: 10.1172/jci.insight.137230. JCI Insight. 2020. PMID: 32641586 Free PMC article.
Hematopoietic defects in response to reduced Arhgap21.
Xavier-Ferrucio J, Ricon L, Vieira K, Longhini AL, Lazarini M, Bigarella CL, Franchi G Jr, Krause DS, Saad STO. Xavier-Ferrucio J, et al. Among authors: longhini al. Stem Cell Res. 2018 Jan;26:17-27. doi: 10.1016/j.scr.2017.11.014. Epub 2017 Nov 23. Stem Cell Res. 2018. PMID: 29212046 Free PMC article.
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Roversi FM, Pericole FV, Machado-Neto JA, da Silva Santos Duarte A, Longhini AL, Corrocher FA, Palodetto B, Ferro KP, Rosa RG, Baratti MO, Verjovski-Almeida S, Traina F, Molinari A, Botta M, Saad ST. Roversi FM, et al. Among authors: longhini al. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):450-461. doi: 10.1016/j.bbadis.2016.11.013. Epub 2016 Nov 11. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27840303 Free article.
Up-regulation of SPINT2/HAI-2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion.
Roversi FM, Cury NM, Lopes MR, Ferro KP, Machado-Neto JA, Alvarez MC, Dos Santos GP, Giardini Rosa R, Longhini AL, Duarte ADSS, Pericole FV, Favaro P, Yunes JA, Saad STO. Roversi FM, et al. Among authors: longhini al. J Cell Mol Med. 2019 Feb;23(2):1562-1571. doi: 10.1111/jcmm.14066. Epub 2018 Nov 28. J Cell Mol Med. 2019. PMID: 30484958 Free PMC article.
Interferon response and epigenetic modulation by SMARCA4 mutations drive ovarian tumor immunogenicity.
Brodeur MN, Dopeso H, Zhu Y, Longhini ALF, Gazzo A, Sun S, Koche R, Qu R, Hamard PJ, Bykov Y, Green H, Chiappinelli KB, Ozsoy MA, Basili T, Gardner R, Walderich S, DeStanchina E, Greenbaum B, Gönen M, Weigelt B, Zamarin D. Brodeur MN, et al. Among authors: longhini alf. bioRxiv [Preprint]. 2023 Aug 11:2023.08.08.552544. doi: 10.1101/2023.08.08.552544. bioRxiv. 2023. PMID: 37609261 Free PMC article. Preprint.
39 results