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Trauma-induced heme release increases susceptibility to bacterial infection.
Lee GR, Gallo D, Alves de Souza RW, Tiwari-Heckler S, Csizmadia E, Harbison JD, Shankar S, Banner-Goodspeed V, Yaffe MB, Longhi MS, Hauser CJ, Otterbein LE. Lee GR, et al. Among authors: longhi ms. JCI Insight. 2021 Oct 22;6(20):e150813. doi: 10.1172/jci.insight.150813. JCI Insight. 2021. PMID: 34520397 Free PMC article.
Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.
Longhi MS, Vuerich M, Kalbasi A, Kenison JE, Yeste A, Csizmadia E, Vaughn B, Feldbrugge L, Mitsuhashi S, Wegiel B, Otterbein L, Moss A, Quintana FJ, Robson SC. Longhi MS, et al. JCI Insight. 2017 May 4;2(9):e92791. doi: 10.1172/jci.insight.92791. eCollection 2017 May 4. JCI Insight. 2017. PMID: 28469075 Free PMC article.
Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn's Disease.
Feldbrügge L, Moss AC, Yee EU, Csizmadia E, Mitsuhashi S, Longhi MS, Sandhu B, Stephan H, Wu Y, Cheifetz AS, Müller CE, Sévigny J, Robson SC, Jiang ZG. Feldbrügge L, et al. Among authors: longhi ms. J Crohns Colitis. 2017 Sep 1;11(9):1113-1123. doi: 10.1093/ecco-jcc/jjx058. J Crohns Colitis. 2017. PMID: 28472257 Free PMC article.
CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury.
Savio LEB, de Andrade Mello P, Figliuolo VR, de Avelar Almeida TF, Santana PT, Oliveira SDS, Silva CLM, Feldbrügge L, Csizmadia E, Minshall RD, Longhi MS, Wu Y, Robson SC, Coutinho-Silva R. Savio LEB, et al. Among authors: longhi ms. J Hepatol. 2017 Oct;67(4):716-726. doi: 10.1016/j.jhep.2017.05.021. Epub 2017 May 26. J Hepatol. 2017. PMID: 28554875 Free PMC article.
HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease.
Xie A, Robles RJ, Mukherjee S, Zhang H, Feldbrügge L, Csizmadia E, Wu Y, Enjyoji K, Moss AC, Otterbein LE, Quintana FJ, Robson SC, Longhi MS. Xie A, et al. Among authors: longhi ms. J Autoimmun. 2018 Nov;94:122-133. doi: 10.1016/j.jaut.2018.07.022. Epub 2018 Aug 8. J Autoimmun. 2018. PMID: 30098863 Free PMC article.
94 results