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Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery.
PLoS One. 2018 Sep 13;13(9):e0203795. doi: 10.1371/journal.pone.0203795. eCollection 2018.
PLoS One. 2018.
PMID: 30212506
Free PMC article.
Features of Postoperative Immune Suppression Are Reversible With Interferon Gamma and Independent of Interleukin-6 Pathways.
Longbottom ER, Torrance HD, Owen HC, Fragkou PC, Hinds CJ, Pearse RM, O'Dwyer MJ.
Longbottom ER, et al.
Ann Surg. 2016 Aug;264(2):370-7. doi: 10.1097/SLA.0000000000001484.
Ann Surg. 2016.
PMID: 26445474
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A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery.
Torrance HD, Zhang P, Longbottom ER, Mi Y, Whalley JP, Allcock A, Kwok AJ, Cano-Gamez E, Geoghegan CG, Burnham KL, Antcliffe DB, Davenport EE, Pearse RM, O'Dwyer MJ, Hinds CJ, Knight JC, Gordon AC.
Torrance HD, et al. Among authors: longbottom er.
Ann Surg. 2024 Mar 1;279(3):510-520. doi: 10.1097/SLA.0000000000006050. Epub 2023 Jul 27.
Ann Surg. 2024.
PMID: 37497667
Free PMC article.
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Carbohydrate-responsive element-binding protein (ChREBP) is a negative regulator of ARNT/HIF-1beta gene expression in pancreatic islet beta-cells.
Noordeen NA, Khera TK, Sun G, Longbottom ER, Pullen TJ, da Silva Xavier G, Rutter GA, Leclerc I.
Noordeen NA, et al. Among authors: longbottom er.
Diabetes. 2010 Jan;59(1):153-60. doi: 10.2337/db08-0868. Epub 2009 Oct 15.
Diabetes. 2010.
PMID: 19833882
Free PMC article.
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The effects of inhibiting myosin light chain kinase on contraction and calcium signalling in human and rat myometrium.
Longbottom ER, Luckas MJ, Kupittayanant S, Badrick E, Shmigol T, Wray S.
Longbottom ER, et al.
Pflugers Arch. 2000 Jun;440(2):315-21. doi: 10.1007/s004240000305.
Pflugers Arch. 2000.
PMID: 10898533
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Distribution of the voltage-dependent calcium channel alpha(1A) subunit throughout the mature rat brain and its relationship to neurotransmitter pathways.
Craig PJ, McAinsh AD, McCormack AL, Smith W, Beattie RE, Priestley JV, Yip JL, Averill S, Longbottom ER, Volsen SG.
Craig PJ, et al. Among authors: longbottom er.
J Comp Neurol. 1998 Jul 27;397(2):251-67.
J Comp Neurol. 1998.
PMID: 9658287
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