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The use of transient expression systems for the rapid production of virus-like particles in plants.
Thuenemann EC, Lenzi P, Love AJ, Taliansky M, Bécares M, Zuñiga S, Enjuanes L, Zahmanova GG, Minkov IN, Matić S, Noris E, Meyers A, Hattingh A, Rybicki EP, Kiselev OI, Ravin NV, Eldarov MA, Skryabin KG, Lomonossoff GP. Thuenemann EC, et al. Among authors: lomonossoff gp. Curr Pharm Des. 2013;19(31):5564-73. doi: 10.2174/1381612811319310011. Curr Pharm Des. 2013. PMID: 23394559 Review.
Tandem fusion of hepatitis B core antigen allows assembly of virus-like particles in bacteria and plants with enhanced capacity to accommodate foreign proteins.
Peyret H, Gehin A, Thuenemann EC, Blond D, El Turabi A, Beales L, Clarke D, Gilbert RJ, Fry EE, Stuart DI, Holmes K, Stonehouse NJ, Whelan M, Rosenberg W, Lomonossoff GP, Rowlands DJ. Peyret H, et al. PLoS One. 2015 Apr 1;10(4):e0120751. doi: 10.1371/journal.pone.0120751. eCollection 2015. PLoS One. 2015. PMID: 25830365 Free PMC article.
Synthetic plant virology for nanobiotechnology and nanomedicine.
Steele JFC, Peyret H, Saunders K, Castells-Graells R, Marsian J, Meshcheriakova Y, Lomonossoff GP. Steele JFC, et al. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017 Jul;9(4):e1447. doi: 10.1002/wnan.1447. Epub 2017 Jan 11. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017. PMID: 28078770 Free PMC article. Review.
Encapsidation of Viral RNA in Picornavirales: Studies on Cowpea Mosaic Virus Demonstrate Dependence on Viral Replication.
Kruse I, Peyret H, Saxena P, Lomonossoff GP. Kruse I, et al. J Virol. 2019 Jan 4;93(2):e01520-18. doi: 10.1128/JVI.01520-18. Print 2019 Jan 15. J Virol. 2019. PMID: 30355698 Free PMC article.
RNA-free virus-like particles (empty virus-like particles [eVLPs]) can be generated by transiently coexpressing the RNA-2-encoded coat protein precursor (VP60) with the RNA-1-encoded 24,000-molecular-weight (24K) protease, in the absence of the replication machinery (K. Saunders, …
RNA-free virus-like particles (empty virus-like particles [eVLPs]) can be generated by transiently coexpressing the RNA-2-encoded coat prote …
Investigating the Biological Relevance of In Vitro-Identified Putative Packaging Signals at the 5' Terminus of Satellite Tobacco Necrosis Virus 1 Genomic RNA.
Kotta-Loizou I, Peyret H, Saunders K, Coutts RHA, Lomonossoff GP. Kotta-Loizou I, et al. J Virol. 2019 Apr 17;93(9):e02106-18. doi: 10.1128/JVI.02106-18. Print 2019 May 1. J Virol. 2019. PMID: 30814279 Free PMC article.
Satellite tobacco necrosis virus 1 (STNV-1) is a model system for in vitro RNA encapsidation studies (N. Patel, E. C. Dykeman, R. H. A. Coutts, G. P. Lomonossoff, et al., Proc Natl Acad Sci U S A 112:2227-2232, 2015, https://doi.org/10.1073/pnas.1420812112; N. ...Re …
Satellite tobacco necrosis virus 1 (STNV-1) is a model system for in vitro RNA encapsidation studies (N. Patel, E. C. Dykeman, R. H. A. Cout …
203 results