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Drosophila dyskerin is required for somatic stem cell homeostasis.
Vicidomini R, Petrizzo A, di Giovanni A, Cassese L, Lombardi AA, Pragliola C, Furia M. Vicidomini R, et al. Among authors: lombardi aa. Sci Rep. 2017 Mar 23;7(1):347. doi: 10.1038/s41598-017-00446-8. Sci Rep. 2017. PMID: 28337032 Free PMC article.
The transcription factor OCT6 promotes the dissolution of the naïve pluripotent state by repressing Nanog and activating a formative state gene regulatory network.
Waisman A, Sevlever F, Saulnier D, Francia M, Blanco R, Amín G, Lombardi A, Biani C, Palma MB, Scarafía A, Smucler J, La Greca A, Moro L, Sevlever G, Guberman A, Miriuka S. Waisman A, et al. Sci Rep. 2024 May 7;14(1):10420. doi: 10.1038/s41598-024-59247-5. Sci Rep. 2024. PMID: 38710730 Free PMC article.
Glutamine uptake and catabolism is required for myofibroblast formation and persistence.
Gibb AA, Huynh AT, Gaspar RB, Ploesch TL, Lombardi AA, Lorkiewicz PK, Lazaropoulos MP, Bedi K, Arany Z, Margulies KB, Hill BG, Elrod JW. Gibb AA, et al. Among authors: lombardi aa. J Mol Cell Cardiol. 2022 Nov;172:78-89. doi: 10.1016/j.yjmcc.2022.08.002. Epub 2022 Aug 18. J Mol Cell Cardiol. 2022. PMID: 35988357 Free PMC article.
Glutaminolysis is Essential for Myofibroblast Persistence and In Vivo Targeting Reverses Fibrosis and Cardiac Dysfunction in Heart Failure.
Gibb AA, Murray EK, Huynh AT, Gaspar RB, Ploesch TL, Bedi K, Lombardi AA, Lorkiewicz PK, Roy R, Arany Z, Kelly DP, Margulies KB, Hill BG, Elrod JW. Gibb AA, et al. Among authors: lombardi aa. Circulation. 2022 May 24;145(21):1625-1628. doi: 10.1161/CIRCULATIONAHA.121.057879. Epub 2022 May 23. Circulation. 2022. PMID: 35605036 Free PMC article. No abstract available.
Mediating ER-mitochondrial cross-talk.
Lombardi AA, Elrod JW. Lombardi AA, et al. Science. 2017 Nov 3;358(6363):591-592. doi: 10.1126/science.aaq0141. Science. 2017. PMID: 29097535 Free PMC article. No abstract available.
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability.
Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW. Luongo TS, et al. Among authors: lombardi aa. Nature. 2017 May 4;545(7652):93-97. doi: 10.1038/nature22082. Epub 2017 Apr 26. Nature. 2017. PMID: 28445457 Free PMC article.
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