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Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo.
Ramos TL, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn B, Su LL, Picton LK, Baker J, Lohmeyer JK, Riddle M, Eide C, Tolar J, Panoskaltsis-Mortari A, Wagner JE, Garcia KC, Negrin RS, Blazar BR. Ramos TL, et al. Among authors: lohmeyer jk. Blood. 2023 Mar 16;141(11):1337-1352. doi: 10.1182/blood.2022018440. Blood. 2023. PMID: 36564052 Free PMC article.
Molecular Imaging of Chimeric Antigen Receptor T Cells by ICOS-ImmunoPET.
Simonetta F, Alam IS, Lohmeyer JK, Sahaf B, Good Z, Chen W, Xiao Z, Hirai T, Scheller L, Engels P, Vermesh O, Robinson E, Haywood T, Sathirachinda A, Baker J, Malipatlolla MB, Schultz LM, Spiegel JY, Lee JT, Miklos DB, Mackall CL, Gambhir SS, Negrin RS. Simonetta F, et al. Among authors: lohmeyer jk. Clin Cancer Res. 2021 Feb 15;27(4):1058-1068. doi: 10.1158/1078-0432.CCR-20-2770. Epub 2020 Oct 21. Clin Cancer Res. 2021. PMID: 33087332 Free PMC article.
Selective expansion of regulatory T cells using an orthogonal IL-2/IL-2 receptor system facilitates transplantation tolerance.
Hirai T, Ramos TL, Lin PY, Simonetta F, Su LL, Picton LK, Baker J, Lin JX, Li P, Seo K, Lohmeyer JK, Bolivar-Wagers S, Mavers M, Leonard WJ, Blazar BR, Garcia KC, Negrin RS. Hirai T, et al. Among authors: lohmeyer jk. J Clin Invest. 2021 Apr 15;131(8):e139991. doi: 10.1172/JCI139991. J Clin Invest. 2021. PMID: 33855972 Free PMC article.
Invariant natural killer T-cell subsets have diverse graft-versus-host-disease-preventing and antitumor effects.
Maas-Bauer K, Lohmeyer JK, Hirai T, Ramos TL, Fazal FM, Litzenburger UM, Yost KE, Ribado JV, Kambham N, Wenokur AS, Lin PY, Alvarez M, Mavers M, Baker J, Bhatt AS, Chang HY, Simonetta F, Negrin RS. Maas-Bauer K, et al. Among authors: lohmeyer jk. Blood. 2021 Sep 9;138(10):858-870. doi: 10.1182/blood.2021010887. Blood. 2021. PMID: 34036317 Free PMC article.
Extracellular release of mitochondria induced by pre-hematopoietic stem cell transplant conditioning exacerbates GVHD.
Vijayan V, Yan H, Lohmeyer JK, Prentiss KA, Patil RV, Barbarito G, Lopez I, Elezaby A, Peterson K, Baker J, Ostberg NP, Bertaina A, Negrin RS, Mochly-Rosen D, Weinberg KI, Haileselassie B. Vijayan V, et al. Among authors: lohmeyer jk. Blood Adv. 2024 May 3:bloodadvances.2023012328. doi: 10.1182/bloodadvances.2023012328. Online ahead of print. Blood Adv. 2024. PMID: 38701354