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Page 1
Uphold the nuclear weapons test moratorium.
King J, Chalfie M, Chomsky N, Cirincione J, Decatur S, Franklin M, Gerson J, Goldenberg DP, Goldstein G, Hartung W, Helfand I, Holz D, Kahn PC, Krimsky S, Loechler E, Moghadam V, Newman SA, Ozonoff D, Parthasarathi P, Phillips W, Politzer HD, Redwine RP, Roberts RJ, Robock A, Royer CA, Scarlata S, Scarry E, Smoot GF, Socolow R, Solomon S, Strominger A, Sundberg EJ, Sur M, Tegmark M, Tierney JF, van der Ziel C, VanElzakker M, von Hippel FN, Wittner L, Wortis HH. King J, et al. Among authors: loechler e. Science. 2020 Jul 17;369(6501):262. doi: 10.1126/science.abd3313. Science. 2020. PMID: 32675367 No abstract available.
Science for the people.
Schneider S, Loechler E, King J, Beckwith J. Schneider S, et al. Among authors: loechler e. Nature. 1978 Aug 24;274(5673):732. doi: 10.1038/274732a0. Nature. 1978. PMID: 683313 No abstract available.
AP sites are not significantly involved in mutagenesis by the (+)-anti diol epoxide of benzo[a]pyrene: the complexity of its mutagenic specificity is likely to arise from adduct conformational polymorphism.
Drouin EE, Loechler EL. Drouin EE, et al. Among authors: loechler el. Biochemistry. 1993 Jul 6;32(26):6555-62. doi: 10.1021/bi00077a009. Biochemistry. 1993. PMID: 7687146
In previous work, mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] were scored in the supF gene of the Escherichia coli plasmid pUB3 [Rodriguez & Loechler (1993) Biochemistry 32, 1759]. pUB3 was reacted with (+)-anti-B[a]PDE and then …
In previous work, mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] were scored in the supF gene of the Es …
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide can be unstable in double-stranded DNA.
Drouin EE, Lech J, Loechler EL. Drouin EE, et al. Among authors: loechler el. Biochemistry. 1995 Feb 21;34(7):2251-9. doi: 10.1021/bi00007a020. Biochemistry. 1995. PMID: 7857936
The mechanisms of mutagenesis by the (+)-anti diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] was investigated in supF of the Escherichia coli plasmid pUB3 [Rodriguez & Loechler (1993) Biochemistry 32, 1759]. pUB3 was reacted with (+)-anti-B[a]PDE, then either (1) tr …
The mechanisms of mutagenesis by the (+)-anti diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] was investigated in supF of the Escherichia …
The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
Jelinsky SA, Liu T, Geacintov NE, Loechler EL. Jelinsky SA, et al. Among authors: loechler el. Biochemistry. 1995 Oct 17;34(41):13545-53. doi: 10.1021/bi00041a034. Biochemistry. 1995. PMID: 7577943
Mutations induced by the (+)-anti-diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] were collected in the supF gene of the Escherichia coli plasmid pUB3. pUB3 was reacted with (+)-anti-B[a]-PDE and then either (1) transformed immediately into E. coli or (2) heated at 80 de …
Mutations induced by the (+)-anti-diol epoxide of benzo[a]pyrene [(+)-anti-B[a]PDE] were collected in the supF gene of the Escherichia coli …
Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity?
Rodriguez H, Loechler EL. Rodriguez H, et al. Among authors: loechler el. Biochemistry. 1993 Feb 23;32(7):1759-69. doi: 10.1021/bi00058a009. Biochemistry. 1993. PMID: 8439538
The work described herein is an extension of previous work, which involved plasmid adduction and then immediate transformation (Rodriguez & Loechler, 1993), and began with the observation that mutation frequency (MF) decreased approximately 2-fold when the (+)-anti-B[a …
The work described herein is an extension of previous work, which involved plasmid adduction and then immediate transformation (Rodriguez &a …
67 results