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Decreased LIN28B in preeclampsia impairs human trophoblast differentiation and migration.
Canfield J, Arlier S, Mong EF, Lockhart J, VanWye J, Guzeloglu-Kayisli O, Schatz F, Magness RR, Lockwood CJ, Tsibris JCM, Kayisli UA, Totary-Jain H. Canfield J, et al. Among authors: lockhart j. FASEB J. 2019 Feb;33(2):2759-2769. doi: 10.1096/fj.201801163R. Epub 2018 Oct 11. FASEB J. 2019. PMID: 30307771 Free PMC article.
These results provide the first evidence that LIN28B is the predominant paralog in human placenta and that decreased LIN28B may play a role in PE by reducing trophoblast invasion and syncytialization, and by promoting inflammation.-Canfield, J., Arlier, S., Mong, E. F., …
These results provide the first evidence that LIN28B is the predominant paralog in human placenta and that decreased LIN28B may play a role …
Anticipating designer drug-resistant cancer cells.
Frangione ML, Lockhart JH, Morton DT, Pava LM, Blanck G. Frangione ML, et al. Drug Discov Today. 2015 Jul;20(7):790-3. doi: 10.1016/j.drudis.2015.02.005. Epub 2015 Feb 16. Drug Discov Today. 2015. PMID: 25697478 Review.
SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas.
Wickramage I, VanWye J, Max K, Lockhart JH, Hortu I, Mong EF, Canfield J, Lamabadu Warnakulasuriya Patabendige HM, Guzeloglu-Kayisli O, Inoue K, Ogura A, Lockwood CJ, Akat KM, Tuschl T, Kayisli UA, Totary-Jain H. Wickramage I, et al. Among authors: lockhart jh. Cell Host Microbe. 2023 Jul 12;31(7):1185-1199.e10. doi: 10.1016/j.chom.2023.05.018. Epub 2023 Jun 13. Cell Host Microbe. 2023. PMID: 37315561
Deep Learning of Histopathology Images at the Single Cell Level.
Lee K, Lockhart JH, Xie M, Chaudhary R, Slebos RJC, Flores ER, Chung CH, Tan AC. Lee K, et al. Among authors: lockhart jh. Front Artif Intell. 2021 Sep 10;4:754641. doi: 10.3389/frai.2021.754641. eCollection 2021. Front Artif Intell. 2021. PMID: 34568816 Free PMC article. Review.
536 results