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Drug Design Strategies to Avoid Resistance in Direct-Acting Antivirals and Beyond.
Matthew AN, Leidner F, Lockbaum GJ, Henes M, Zephyr J, Hou S, Rao DN, Timm J, Rusere LN, Ragland DA, Paulsen JL, Prachanronarong K, Soumana DI, Nalivaika EA, Kurt Yilmaz N, Ali A, Schiffer CA. Matthew AN, et al. Among authors: lockbaum gj. Chem Rev. 2021 Mar 24;121(6):3238-3270. doi: 10.1021/acs.chemrev.0c00648. Epub 2021 Jan 7. Chem Rev. 2021. PMID: 33410674 Free PMC article. Review.
Picomolar to Micromolar: Elucidating the Role of Distal Mutations in HIV-1 Protease in Conferring Drug Resistance.
Henes M, Lockbaum GJ, Kosovrasti K, Leidner F, Nachum GS, Nalivaika EA, Lee SK, Spielvogel E, Zhou S, Swanstrom R, Bolon DNA, Kurt Yilmaz N, Schiffer CA. Henes M, et al. Among authors: lockbaum gj. ACS Chem Biol. 2019 Nov 15;14(11):2441-2452. doi: 10.1021/acschembio.9b00370. Epub 2019 Aug 13. ACS Chem Biol. 2019. PMID: 31361460 Free PMC article.
Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere.
Rusere LN, Lockbaum GJ, Henes M, Lee SK, Spielvogel E, Rao DN, Kosovrasti K, Nalivaika EA, Swanstrom R, Kurt Yilmaz N, Schiffer CA, Ali A. Rusere LN, et al. Among authors: lockbaum gj. J Med Chem. 2020 Aug 13;63(15):8296-8313. doi: 10.1021/acs.jmedchem.0c00529. Epub 2020 Aug 3. J Med Chem. 2020. PMID: 32672965 Free PMC article.
18 results