Lock RB - Search Results

1

High-Throughput Drug Screening of Primary Tumor Cells Identifies Therapeutic Strategies for Treating Children with High-Risk Cancer.

Mayoh C, Mao J, Xie J, Tax G, Chow SO, Cadiz R, Pazaky K, Barahona P, Ajuyah P, Trebilcock P, Malquori A, Gunther K, Avila A, Yun DY, Alfred S, Gopalakrishnan A, Kamili A, Wong M, Cowley MJ, Jessop S, Lau LMS, Trahair TN, Ziegler DS, Fletcher JI, Gifford AJ, Tsoli M, Marshall GM, Haber M, Tyrrell V, Failes TW, Arndt GM, Lock RB, Ekert PG, Dolman MEM. Mayoh C, et al. Among authors: lock rb. Cancer Res. 2023 Aug 15;83(16):2716-2732. doi: 10.1158/0008-5472.CAN-22-3702. Cancer Res. 2023. PMID: 37523146 Free PMC article.

2

High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

Catts VS, Farnsworth ML, Haber M, Norris MD, Lutze-Mann LH, Lock RB. Catts VS, et al. Among authors: lock rb. Leukemia. 2001 Jun;15(6):929-35. doi: 10.1038/sj.leu.2402128. Leukemia. 2001. PMID: 11417479

3

MRP1 gene expression level regulates the death and differentiation response of neuroblastoma cells.

Peaston AE, Gardaneh M, Franco AV, Hocker JE, Murphy KM, Farnsworth ML, Catchpoole DR, Haber M, Norris MD, Lock RB, Marshall GM. Peaston AE, et al. Among authors: lock rb. Br J Cancer. 2001 Nov 16;85(10):1564-71. doi: 10.1054/bjoc.2001.2144. Br J Cancer. 2001. PMID: 11720446 Free PMC article.

4

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

5

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Among authors: lock rb. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

6

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

Bachmann PS, Gorman R, Papa RA, Bardell JE, Ford J, Kees UR, Marshall GM, Lock RB. Bachmann PS, et al. Among authors: lock rb. Cancer Res. 2007 May 1;67(9):4482-90. doi: 10.1158/0008-5472.CAN-06-4244. Cancer Res. 2007. PMID: 17483364

7

p53 determines multidrug sensitivity of childhood neuroblastoma.

Xue C, Haber M, Flemming C, Marshall GM, Lock RB, MacKenzie KL, Gurova KV, Norris MD, Gudkov AV. Xue C, et al. Among authors: lock rb. Cancer Res. 2007 Nov 1;67(21):10351-60. doi: 10.1158/0008-5472.CAN-06-4345. Cancer Res. 2007. PMID: 17974978

8

A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.

Ong V, Liem NL, Schmid MA, Verrills NM, Papa RA, Marshall GM, Mackenzie KL, Kavallaris M, Lock RB. Ong V, et al. Among authors: lock rb. J Pharmacol Exp Ther. 2008 Feb;324(2):434-42. doi: 10.1124/jpet.107.128926. Epub 2007 Nov 6. J Pharmacol Exp Ther. 2008. PMID: 17986648

9

Glucocorticoid resistance in paediatric acute lymphoblastic leukaemia.

Bhadri VA, Trahair TN, Lock RB. Bhadri VA, et al. Among authors: lock rb. J Paediatr Child Health. 2012 Aug;48(8):634-40. doi: 10.1111/j.1440-1754.2011.02212.x. Epub 2011 Nov 3. J Paediatr Child Health. 2012. PMID: 22050419 Review.

10

Evaluation of the NOD/SCID xenograft model for glucocorticoid-regulated gene expression in childhood B-cell precursor acute lymphoblastic leukemia.

Bhadri VA, Cowley MJ, Kaplan W, Trahair TN, Lock RB. Bhadri VA, et al. Among authors: lock rb. BMC Genomics. 2011 Nov 17;12:565. doi: 10.1186/1471-2164-12-565. BMC Genomics. 2011. PMID: 22093874 Free PMC article.

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