Lock RB - Search Results

1

Delivery of PEGylated liposomal doxorubicin by bispecific antibodies improves treatment in models of high-risk childhood leukemia.

Moles E, Howard CB, Huda P, Karsa M, McCalmont H, Kimpton K, Duly A, Chen Y, Huang Y, Tursky ML, Ma D, Bustamante S, Pickford R, Connerty P, Omari S, Jolly CJ, Joshi S, Shen S, Pimanda JE, Dolnikov A, Cheung LC, Kotecha RS, Norris MD, Haber M, de Bock CE, Somers K, Lock RB, Thurecht KJ, Kavallaris M. Moles E, et al. Among authors: lock rb. Sci Transl Med. 2023 May 17;15(696):eabm1262. doi: 10.1126/scitranslmed.abm1262. Epub 2023 May 17. Sci Transl Med. 2023. PMID: 37196067

2

High level resistance to glucocorticoids, associated with a dysfunctional glucocorticoid receptor, in childhood acute lymphoblastic leukemia cells selected for methotrexate resistance.

Catts VS, Farnsworth ML, Haber M, Norris MD, Lutze-Mann LH, Lock RB. Catts VS, et al. Among authors: lock rb. Leukemia. 2001 Jun;15(6):929-35. doi: 10.1038/sj.leu.2402128. Leukemia. 2001. PMID: 11417479

3

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.

Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813 Free article.

4

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies.

Liem NL, Papa RA, Milross CG, Schmid MA, Tajbakhsh M, Choi S, Ramirez CD, Rice AM, Haber M, Norris MD, MacKenzie KL, Lock RB. Liem NL, et al. Among authors: lock rb. Blood. 2004 May 15;103(10):3905-14. doi: 10.1182/blood-2003-08-2911. Epub 2004 Feb 5. Blood. 2004. PMID: 14764536 Free article.

5

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.

Verrills NM, Liem NL, Liaw TY, Hood BD, Lock RB, Kavallaris M. Verrills NM, et al. Among authors: lock rb. Proteomics. 2006 Mar;6(5):1681-94. doi: 10.1002/pmic.200500417. Proteomics. 2006. PMID: 16456880

6

The role of IRF1 and IRF2 transcription factors in leukaemogenesis.

Choo A, Palladinetti P, Passioura T, Shen S, Lock R, Symonds G, Dolnikov A. Choo A, et al. Curr Gene Ther. 2006 Oct;6(5):543-50. doi: 10.2174/156652306778520683. Curr Gene Ther. 2006. PMID: 17073600 Review.

7

p53 determines multidrug sensitivity of childhood neuroblastoma.

Xue C, Haber M, Flemming C, Marshall GM, Lock RB, MacKenzie KL, Gurova KV, Norris MD, Gudkov AV. Xue C, et al. Among authors: lock rb. Cancer Res. 2007 Nov 1;67(21):10351-60. doi: 10.1158/0008-5472.CAN-06-4345. Cancer Res. 2007. PMID: 17974978

8

A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.

Ong V, Liem NL, Schmid MA, Verrills NM, Papa RA, Marshall GM, Mackenzie KL, Kavallaris M, Lock RB. Ong V, et al. Among authors: lock rb. J Pharmacol Exp Ther. 2008 Feb;324(2):434-42. doi: 10.1124/jpet.107.128926. Epub 2007 Nov 6. J Pharmacol Exp Ther. 2008. PMID: 17986648

9

siRNA targeting the IRF2 transcription factor inhibits leukaemic cell growth.

Choo A, Palladinetti P, Holmes T, Basu S, Shen S, Lock RB, O'Brien TA, Symonds G, Dolnikov A. Choo A, et al. Among authors: lock rb. Int J Oncol. 2008 Jul;33(1):175-83. Int J Oncol. 2008. PMID: 18575764

10

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

Bachmann PS, Piazza RG, Janes ME, Wong NC, Davies C, Mogavero A, Bhadri VA, Szymanska B, Geninson G, Magistroni V, Cazzaniga G, Biondi A, Miranda-Saavedra D, Göttgens B, Saffery R, Craig JM, Marshall GM, Gambacorti-Passerini C, Pimanda JE, Lock RB. Bachmann PS, et al. Among authors: lock rb. Blood. 2010 Oct 21;116(16):3013-22. doi: 10.1182/blood-2010-05-284968. Epub 2010 Jul 20. Blood. 2010. PMID: 20647567 Free article.

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