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Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection.
Wettstein L, Weil T, Conzelmann C, Müller JA, Groß R, Hirschenberger M, Seidel A, Klute S, Zech F, Prelli Bozzo C, Preising N, Fois G, Lochbaum R, Knaff PM, Mailänder V, Ständker L, Thal DR, Schumann C, Stenger S, Kleger A, Lochnit G, Mayer B, Ruiz-Blanco YB, Hoffmann M, Sparrer KMJ, Pöhlmann S, Sanchez-Garcia E, Kirchhoff F, Frick M, Münch J. Wettstein L, et al. Among authors: lochnit g. Nat Commun. 2021 Mar 19;12(1):1726. doi: 10.1038/s41467-021-21972-0. Nat Commun. 2021. PMID: 33741941 Free PMC article.
IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Steffen U, Koeleman CA, Sokolova MV, Bang H, Kleyer A, Rech J, Unterweger H, Schicht M, Garreis F, Hahn J, Andes FT, Hartmann F, Hahn M, Mahajan A, Paulsen F, Hoffmann M, Lochnit G, Muñoz LE, Wuhrer M, Falck D, Herrmann M, Schett G. Steffen U, et al. Among authors: lochnit g. Nat Commun. 2020 Jan 8;11(1):120. doi: 10.1038/s41467-019-13992-8. Nat Commun. 2020. PMID: 31913287 Free PMC article.
Caspase-11 promotes allergic airway inflammation.
Zasłona Z, Flis E, Wilk MM, Carroll RG, Palsson-McDermott EM, Hughes MM, Diskin C, Banahan K, Ryan DG, Hooftman A, Misiak A, Kearney J, Lochnit G, Bertrams W, Greulich T, Schmeck B, McElvaney OJ, Mills KHG, Lavelle EC, Wygrecka M, Creagh EM, O'Neill LAJ. Zasłona Z, et al. Among authors: lochnit g. Nat Commun. 2020 Feb 26;11(1):1055. doi: 10.1038/s41467-020-14945-2. Nat Commun. 2020. PMID: 32103022 Free PMC article.
Complement Activation in Kidneys of Patients With COVID-19.
Pfister F, Vonbrunn E, Ries T, Jäck HM, Überla K, Lochnit G, Sheriff A, Herrmann M, Büttner-Herold M, Amann K, Daniel C. Pfister F, et al. Among authors: lochnit g. Front Immunol. 2021 Jan 29;11:594849. doi: 10.3389/fimmu.2020.594849. eCollection 2020. Front Immunol. 2021. PMID: 33584662 Free PMC article.
Citrullination Licenses Calpain to Decondense Nuclei in Neutrophil Extracellular Trap Formation.
Gößwein S, Lindemann A, Mahajan A, Maueröder C, Martini E, Patankar J, Schett G, Becker C, Wirtz S, Naumann-Bartsch N, Bianchi ME, Greer PA, Lochnit G, Herrmann M, Neurath MF, Leppkes M. Gößwein S, et al. Among authors: lochnit g. Front Immunol. 2019 Oct 22;10:2481. doi: 10.3389/fimmu.2019.02481. eCollection 2019. Front Immunol. 2019. PMID: 31695698 Free PMC article.
127 results