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Targeting Ion Channel TRPM4.
Preti B, Rougier JS, Papapostolou I, Bochen F, Gerber CE, Abriel H, Lochner M, Peinelt C. Preti B, et al. Among authors: lochner m. Chimia (Aarau). 2022 Dec 21;76(12):1039-1044. doi: 10.2533/chimia.2022.1039. Chimia (Aarau). 2022. PMID: 38069800 Free article.
Identification of potent and selective small molecule inhibitors of the cation channel TRPM4.
Ozhathil LC, Delalande C, Bianchi B, Nemeth G, Kappel S, Thomet U, Ross-Kaschitza D, Simonin C, Rubin M, Gertsch J, Lochner M, Peinelt C, Reymond JL, Abriel H. Ozhathil LC, et al. Among authors: lochner m. Br J Pharmacol. 2018 Jun;175(12):2504-2519. doi: 10.1111/bph.14220. Epub 2018 Apr 29. Br J Pharmacol. 2018. PMID: 29579323 Free PMC article.
Species-Specific Effects of Cation Channel TRPM4 Small-Molecule Inhibitors.
Arullampalam P, Preti B, Ross-Kaschitza D, Lochner M, Rougier JS, Abriel H. Arullampalam P, et al. Among authors: lochner m. Front Pharmacol. 2021 Jul 12;12:712354. doi: 10.3389/fphar.2021.712354. eCollection 2021. Front Pharmacol. 2021. PMID: 34335274 Free PMC article.
Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.
Schild A, Bhardwaj R, Wenger N, Tscherrig D, Kandasamy P, Dernič J, Baur R, Peinelt C, Hediger MA, Lochner M. Schild A, et al. Among authors: lochner m. Int J Mol Sci. 2020 Aug 5;21(16):5604. doi: 10.3390/ijms21165604. Int J Mol Sci. 2020. PMID: 32764353 Free PMC article.
Deciphering the Agonist Binding Mechanism to the Adenosine A1 Receptor.
Deganutti G, Barkan K, Preti B, Leuenberger M, Wall M, Frenguelli BG, Lochner M, Ladds G, Reynolds CA. Deganutti G, et al. Among authors: lochner m. ACS Pharmacol Transl Sci. 2021 Jan 21;4(1):314-326. doi: 10.1021/acsptsci.0c00195. eCollection 2021 Feb 12. ACS Pharmacol Transl Sci. 2021. PMID: 33615181 Free PMC article.
107 results