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Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D. Luther A, et al. Among authors: locher hh. Nature. 2019 Dec;576(7787):452-458. doi: 10.1038/s41586-019-1665-6. Epub 2019 Oct 23. Nature. 2019. PMID: 31645764
Synthesis and Characterization of Tetrahydropyran-Based Bacterial Topoisomerase Inhibitors with Antibacterial Activity against Gram-Negative Bacteria.
Surivet JP, Zumbrunn C, Bruyère T, Bur D, Kohl C, Locher HH, Seiler P, Ertel EA, Hess P, Enderlin-Paput M, Enderlin-Paput S, Gauvin JC, Mirre A, Hubschwerlen C, Ritz D, Rueedi G. Surivet JP, et al. Among authors: locher hh. J Med Chem. 2017 May 11;60(9):3776-3794. doi: 10.1021/acs.jmedchem.6b01831. Epub 2017 Apr 24. J Med Chem. 2017. PMID: 28406300
Author Correction: Chimeric peptidomimetic antibiotics against Gram-negative bacteria.
Luther A, Urfer M, Zahn M, Müller M, Wang SY, Mondal M, Vitale A, Hartmann JB, Sharpe T, Monte FL, Kocherla H, Cline E, Pessi G, Rath P, Modaresi SM, Chiquet P, Stiegeler S, Verbree C, Remus T, Schmitt M, Kolopp C, Westwood MA, Desjonquères N, Brabet E, Hell S, LePoupon K, Vermeulen A, Jaisson R, Rithié V, Upert G, Lederer A, Zbinden P, Wach A, Moehle K, Zerbe K, Locher HH, Bernardini F, Dale GE, Eberl L, Wollscheid B, Hiller S, Robinson JA, Obrecht D. Luther A, et al. Among authors: locher hh. Nature. 2019 Dec;576(7786):E5. doi: 10.1038/s41586-019-1810-2. Nature. 2019. PMID: 31758154
Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Schuster M, Brabet E, Oi KK, Desjonquères N, Moehle K, Le Poupon K, Hell S, Gable S, Rithié V, Dillinger S, Zbinden P, Luther A, Li C, Stiegeler S, D'Arco C, Locher H, Remus T, DiMaio S, Motta P, Wach A, Jung F, Upert G, Obrecht D, Benghezal M, Zerbe O. Schuster M, et al. Sci Adv. 2023 May 24;9(21):eadg3683. doi: 10.1126/sciadv.adg3683. Epub 2023 May 24. Sci Adv. 2023. PMID: 37224246 Free PMC article.
Dimers of nostocarboline with potent antibacterial activity.
Locher HH, Ritz D, Pfaff P, Gaertner M, Knezevic A, Sabato D, Schroeder S, Barbaras D, Gademann K. Locher HH, et al. Chemotherapy. 2010;56(4):318-24. doi: 10.1159/000320033. Epub 2010 Aug 13. Chemotherapy. 2010. PMID: 20714150 Free article.
Design, synthesis, and characterization of novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram-positive activity.
Surivet JP, Zumbrunn C, Rueedi G, Hubschwerlen C, Bur D, Bruyère T, Locher H, Ritz D, Keck W, Seiler P, Kohl C, Gauvin JC, Mirre A, Kaegi V, Dos Santos M, Gaertner M, Delers J, Enderlin-Paput M, Boehme M. Surivet JP, et al. J Med Chem. 2013 Sep 26;56(18):7396-415. doi: 10.1021/jm400963y. Epub 2013 Sep 11. J Med Chem. 2013. PMID: 23968485
36 results