The dynamic adaptation of primary human endothelial cells to simulated microgravity.
Cazzaniga A, Locatelli L, Castiglioni S, Maier JAM.
Cazzaniga A, et al. Among authors: locatelli l.
FASEB J. 2019 May;33(5):5957-5966. doi: 10.1096/fj.201801586RR. Epub 2019 Feb 28.
FASEB J. 2019.
PMID: 30817172
Free article.
We conclude that HSP70 up-regulation sustains the initial adaptive response of endothelial cells to mechanical unloading and drives them toward the acquisition of a novel phenotype that maintains cell viability and function through the sequential involvement of different stress p …
We conclude that HSP70 up-regulation sustains the initial adaptive response of endothelial cells to mechanical unloading and drives them tow …