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Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites.
Holdgaard SG, Cianfanelli V, Pupo E, Lambrughi M, Lubas M, Nielsen JC, Eibes S, Maiani E, Harder LM, Wesch N, Foged MM, Maeda K, Nazio F, de la Ballina LR, Dötsch V, Brech A, Frankel LB, Jäättelä M, Locatelli F, Barisic M, Andersen JS, Bekker-Jensen S, Lund AH, Rogov VV, Papaleo E, Lanzetti L, De Zio D, Cecconi F. Holdgaard SG, et al. Among authors: locatelli f. Nat Commun. 2019 Sep 13;10(1):4176. doi: 10.1038/s41467-019-12094-9. Nat Commun. 2019. PMID: 31519908 Free PMC article.
AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis.
Becher J, Simula L, Volpe E, Procaccini C, La Rocca C, D'Acunzo P, Cianfanelli V, Strappazzon F, Caruana I, Nazio F, Weber G, Gigantino V, Botti G, Ciccosanti F, Borsellino G, Campello S, Mandolesi G, De Bardi M, Fimia GM, D'Amelio M, Ruffini F, Furlan R, Centonze D, Martino G, Braghetta P, Chrisam M, Bonaldo P, Matarese G, Locatelli F, Battistini L, Cecconi F. Becher J, et al. Among authors: locatelli f. Dev Cell. 2018 Dec 3;47(5):592-607.e6. doi: 10.1016/j.devcel.2018.11.010. Dev Cell. 2018. PMID: 30513302 Free article.
Reversible induction of mitophagy by an optogenetic bimodular system.
D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, Weber G, Del Bufalo F, Dalla Valle L, Campello S, Locatelli F, Cecconi F. D'Acunzo P, et al. Among authors: locatelli f. Nat Commun. 2019 Apr 4;10(1):1533. doi: 10.1038/s41467-019-09487-1. Nat Commun. 2019. PMID: 30948710 Free PMC article.
HUWE1 controls MCL1 stability to unleash AMBRA1-induced mitophagy.
Strappazzon F, Di Rita A, Peschiaroli A, Leoncini PP, Locatelli F, Melino G, Cecconi F. Strappazzon F, et al. Among authors: locatelli f. Cell Death Differ. 2020 Apr;27(4):1155-1168. doi: 10.1038/s41418-019-0404-8. Epub 2019 Aug 21. Cell Death Differ. 2020. PMID: 31434979 Free PMC article.
JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.
Simula L, Corrado M, Accordi B, Di Rita A, Nazio F, Antonucci Y, Di Daniele A, Caicci F, Caruana I, Soriano ME, Pigazzi M, Locatelli F, Cecconi F, Campello S. Simula L, et al. Among authors: locatelli f. Cell Death Differ. 2020 Oct;27(10):2749-2767. doi: 10.1038/s41418-020-0540-1. Epub 2020 Apr 28. Cell Death Differ. 2020. PMID: 32346136 Free PMC article.
AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani E, Milletti G, Nazio F, Holdgaard SG, Bartkova J, Rizza S, Cianfanelli V, Lorente M, Simoneschi D, Di Marco M, D'Acunzo P, Di Leo L, Rasmussen R, Montagna C, Raciti M, De Stefanis C, Gabicagogeascoa E, Rona G, Salvador N, Pupo E, Merchut-Maya JM, Daniel CJ, Carinci M, Cesarini V, O'sullivan A, Jeong YT, Bordi M, Russo F, Campello S, Gallo A, Filomeni G, Lanzetti L, Sears RC, Hamerlik P, Bartolazzi A, Hynds RE, Pearce DR, Swanton C, Pagano M, Velasco G, Papaleo E, De Zio D, Maya-Mendoza A, Locatelli F, Bartek J, Cecconi F. Maiani E, et al. Among authors: locatelli f. Nature. 2021 Apr;592(7856):799-803. doi: 10.1038/s41586-021-03422-5. Epub 2021 Apr 14. Nature. 2021. PMID: 33854232 Free PMC article.
2,178 results