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Page 1
Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains.
McCulloch LH, Sambasivam V, Hughes AL, Annaluru N, Ramalingam S, Fanfani V, Lobzaev E, Mitchell LA, Cai J; Build-A-Genome Class; Jiang H, LaCava J, Taylor MS, Bishai WR, Stracquadanio G, Steinmetz LM, Bader JS, Zhang W, Boeke JD, Chandrasegaran S. McCulloch LH, et al. Among authors: lobzaev e. Cell Genom. 2023 Nov 9;3(11):100419. doi: 10.1016/j.xgen.2023.100419. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020974 Free PMC article.
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.
Blount BA, Lu X, Driessen MRM, Jovicevic D, Sanchez MI, Ciurkot K, Zhao Y, Lauer S, McKiernan RM, Gowers GF, Sweeney F, Fanfani V, Lobzaev E, Palacios-Flores K, Walker RSK, Hesketh A, Cai J, Oliver SG, Cai Y, Stracquadanio G, Mitchell LA, Bader JS, Boeke JD, Ellis T. Blount BA, et al. Among authors: lobzaev e. Cell Genom. 2023 Nov 9;3(11):100418. doi: 10.1016/j.xgen.2023.100418. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020971 Free PMC article.
Context-dependent neocentromere activity in synthetic yeast chromosome VIII.
Lauer S, Luo J, Lazar-Stefanita L, Zhang W, McCulloch LH, Fanfani V, Lobzaev E, Haase MAB, Easo N, Zhao Y, Yu F, Cai J; Build-A-Genome Class; Bader JS, Stracquadanio G, Boeke JD. Lauer S, et al. Among authors: lobzaev e. Cell Genom. 2023 Nov 9;3(11):100437. doi: 10.1016/j.xgen.2023.100437. eCollection 2023 Nov 8. Cell Genom. 2023. PMID: 38020969 Free PMC article.
Manipulating the 3D organization of the largest synthetic yeast chromosome.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, Easo N, Lin SJ, Camellato BR, Zhu Y, Cai J, Xu Z, Zhao Y, Sacasa M; Build-A-Genome Class; Noyes MB, Bader JS, Deutsch S, Stracquadanio G, Aizawa Y, Dai J, Boeke JD. Zhang W, et al. Among authors: lobzaev e. Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8. Mol Cell. 2023. PMID: 37944526 Free article.
Development and validation of DNA methylation scores in two European cohorts augment 10-year risk prediction of type 2 diabetes.
Cheng Y, Gadd DA, Gieger C, Monterrubio-Gómez K, Zhang Y, Berta I, Stam MJ, Szlachetka N, Lobzaev E, Wrobel N, Murphy L, Campbell A, Nangle C, Walker RM, Fawns-Ritchie C, Peters A, Rathmann W, Porteous DJ, Evans KL, McIntosh AM, Cannings TI, Waldenberger M, Ganna A, McCartney DL, Vallejos CA, Marioni RE. Cheng Y, et al. Among authors: lobzaev e. Nat Aging. 2023 Apr;3(4):450-458. doi: 10.1038/s43587-023-00391-4. Epub 2023 Apr 6. Nat Aging. 2023. PMID: 37117793