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Mirror-image ligand discovery enabled by single-shot fast-flow synthesis of D-proteins.
Callahan AJ, Gandhesiri S, Travaline TL, Reja RM, Lozano Salazar L, Hanna S, Lee YC, Li K, Tokareva OS, Swiecicki JM, Loas A, Verdine GL, McGee JH, Pentelute BL. Callahan AJ, et al. Among authors: loas a. Nat Commun. 2024 Feb 28;15(1):1813. doi: 10.1038/s41467-024-45634-z. Nat Commun. 2024. PMID: 38418820 Free PMC article.
Introduction: Peptide Chemistry.
Loas A, Pentelute BL. Loas A, et al. Chem Rev. 2020 Mar 25;120(6):3049-3050. doi: 10.1021/acs.chemrev.0c00136. Chem Rev. 2020. PMID: 32208601 No abstract available.
Synthesis of proteins by automated flow chemistry.
Hartrampf N, Saebi A, Poskus M, Gates ZP, Callahan AJ, Cowfer AE, Hanna S, Antilla S, Schissel CK, Quartararo AJ, Ye X, Mijalis AJ, Simon MD, Loas A, Liu S, Jessen C, Nielsen TE, Pentelute BL. Hartrampf N, et al. Among authors: loas a. Science. 2020 May 29;368(6494):980-987. doi: 10.1126/science.abb2491. Science. 2020. PMID: 32467387
A reactive peptide interface for site-selective cysteine bioconjugation.
Tuang S , Dieppa-Matos D , Zhang C , Shugrue CR , Dai P , Loas A , Pentelute BL . Tuang S , et al. Among authors: loas a. Chem Commun (Camb). 2021 Apr 4;57(26):3227-3230. doi: 10.1039/d1cc00095k. Epub 2021 Mar 1. Chem Commun (Camb). 2021. PMID: 33645592 Free PMC article.
Oligonucleotide Bioconjugation with Bifunctional Palladium Reagents.
Jbara M, Rodriguez J, Dhanjee HH, Loas A, Buchwald SL, Pentelute BL. Jbara M, et al. Among authors: loas a. Angew Chem Int Ed Engl. 2021 May 17;60(21):12109-12115. doi: 10.1002/anie.202103180. Epub 2021 Apr 16. Angew Chem Int Ed Engl. 2021. PMID: 33730425 Free PMC article.
Fully automated fast-flow synthesis of antisense phosphorodiamidate morpholino oligomers.
Li C, Callahan AJ, Simon MD, Totaro KA, Mijalis AJ, Phadke KS, Zhang G, Hartrampf N, Schissel CK, Zhou M, Zong H, Hanson GJ, Loas A, Pohl NLB, Verhoeven DE, Pentelute BL. Li C, et al. Among authors: loas a. Nat Commun. 2021 Jul 20;12(1):4396. doi: 10.1038/s41467-021-24598-4. Nat Commun. 2021. PMID: 34285203 Free PMC article.
Deep learning to design nuclear-targeting abiotic miniproteins.
Schissel CK, Mohapatra S, Wolfe JM, Fadzen CM, Bellovoda K, Wu CL, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Schissel CK, et al. Among authors: loas a. Nat Chem. 2021 Oct;13(10):992-1000. doi: 10.1038/s41557-021-00766-3. Epub 2021 Aug 9. Nat Chem. 2021. PMID: 34373596 Free PMC article.
An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance.
Loftis AR, Zhang G, Backlund C, Quartararo AJ, Pishesha N, Hanna CC, Schissel CK, Garafola D, Loas A, Collier RJ, Ploegh H, Irvine DJ, Pentelute BL. Loftis AR, et al. Among authors: loas a. Proc Natl Acad Sci U S A. 2021 Aug 24;118(34):e2101596118. doi: 10.1073/pnas.2101596118. Proc Natl Acad Sci U S A. 2021. PMID: 34417313 Free PMC article.
37 results