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Variants of Streptococcus pneumoniae Serotype 14 from Papua New Guinea with the Potential to Be Mistyped and Escape Vaccine-Induced Protection.
Manna S, Spry L, Wee-Hee A, Ortika BD, Boelsen LK, Batinovic S, Mazarakis N, Ford RL, Lo SW, Bentley SD, Russell FM, Blyth CC, Pomat WS, Petrovski S, Hinds J, Licciardi PV, Satzke C. Manna S, et al. Among authors: lo sw. Microbiol Spectr. 2022 Aug 31;10(4):e0152422. doi: 10.1128/spectrum.01524-22. Epub 2022 Jul 12. Microbiol Spectr. 2022. PMID: 35862970 Free PMC article.
Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine.
Lo SW, Gladstone RA, van Tonder AJ, Hawkins PA, Kwambana-Adams B, Cornick JE, Madhi SA, Nzenze SA, du Plessis M, Kandasamy R, Carter PE, Eser ÖK, Ho PL, Elmdaghri N, Shakoor S, Clarke SC, Antonio M, Everett DB, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD. Lo SW, et al. J Clin Microbiol. 2018 Jun 25;56(7):e00228-18. doi: 10.1128/JCM.00228-18. Print 2018 Jul. J Clin Microbiol. 2018. PMID: 29720431 Free PMC article.
Fast and flexible bacterial genomic epidemiology with PopPUNK.
Lees JA, Harris SR, Tonkin-Hill G, Gladstone RA, Lo SW, Weiser JN, Corander J, Bentley SD, Croucher NJ. Lees JA, et al. Among authors: lo sw. Genome Res. 2019 Feb;29(2):304-316. doi: 10.1101/gr.241455.118. Epub 2019 Jan 24. Genome Res. 2019. PMID: 30679308 Free PMC article.
International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
Gladstone RA, Lo SW, Lees JA, Croucher NJ, van Tonder AJ, Corander J, Page AJ, Marttinen P, Bentley LJ, Ochoa TJ, Ho PL, du Plessis M, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium. Gladstone RA, et al. Among authors: lo sw. EBioMedicine. 2019 May;43:338-346. doi: 10.1016/j.ebiom.2019.04.021. Epub 2019 Apr 16. EBioMedicine. 2019. PMID: 31003929 Free PMC article.
Putative novel cps loci in a large global collection of pneumococci.
van Tonder AJ, Gladstone RA, Lo SW, Nahm MH, du Plessis M, Cornick J, Kwambana-Adams B, Madhi SA, Hawkins PA, Benisty R, Dagan R, Everett D, Antonio M, Klugman KP, von Gottberg A, Breiman RF, McGee L, Bentley SD; The Global Pneumococcal Sequencing Consortium. van Tonder AJ, et al. Among authors: lo sw. Microb Genom. 2019 Jul;5(7):e000274. doi: 10.1099/mgen.0.000274. Epub 2019 Jun 11. Microb Genom. 2019. PMID: 31184299 Free PMC article.
Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
Lo SW, Gladstone RA, van Tonder AJ, Lees JA, du Plessis M, Benisty R, Givon-Lavi N, Hawkins PA, Cornick JE, Kwambana-Adams B, Law PY, Ho PL, Antonio M, Everett DB, Dagan R, von Gottberg A, Klugman KP, McGee L, Breiman RF, Bentley SD; Global Pneumococcal Sequencing Consortium. Lo SW, et al. Lancet Infect Dis. 2019 Jul;19(7):759-769. doi: 10.1016/S1473-3099(19)30297-X. Epub 2019 Jun 10. Lancet Infect Dis. 2019. PMID: 31196809 Free PMC article.
A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.
Lo SW, Gladstone RA, van Tonder AJ, Du Plessis M, Cornick JE, Hawkins PA, Madhi SA, Nzenze SA, Kandasamy R, Ravikumar KL, Elmdaghri N, Kwambana-Adams B, Almeida SCG, Skoczynska A, Egorova E, Titov L, Saha SK, Paragi M, Everett DB, Antonio M, Klugman KP, Li Y, Metcalf BJ, Beall B, McGee L, Breiman RF, Bentley SD, von Gottberg A; Global Pneumococcal Sequencing Consortium. Lo SW, et al. J Antimicrob Chemother. 2020 Mar 1;75(3):512-520. doi: 10.1093/jac/dkz477. J Antimicrob Chemother. 2020. PMID: 31789384 Free PMC article.
Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates.
Gladstone RA, Lo SW, Goater R, Yeats C, Taylor B, Hadfield J, Lees JA, Croucher NJ, van Tonder AJ, Bentley LJ, Quah FX, Blaschke AJ, Pershing NL, Byington CL, Balaji V, Hryniewicz W, Sigauque B, Ravikumar KL, Almeida SCG, Ochoa TJ, Ho PL, du Plessis M, Ndlangisa KM, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Pollard AJ, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, Metcalf BJ, Li Y, Beall BW, McGee L, Breiman RF, Aanensen DM, Bentley SD, The Global Pneumococcal Sequencing Consortium. Gladstone RA, et al. Among authors: lo sw. Microb Genom. 2020 May;6(5):e000357. doi: 10.1099/mgen.0.000357. Epub 2020 Apr 29. Microb Genom. 2020. PMID: 32375991 Free PMC article.
Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation.
Chaguza C, Senghore M, Bojang E, Gladstone RA, Lo SW, Tientcheu PE, Bancroft RE, Worwui A, Foster-Nyarko E, Ceesay F, Okoi C, McGee L, Klugman KP, Breiman RF, Barer MR, Adegbola RA, Antonio M, Bentley SD, Kwambana-Adams BA. Chaguza C, et al. Among authors: lo sw. Nat Commun. 2020 Jul 10;11(1):3442. doi: 10.1038/s41467-020-17327-w. Nat Commun. 2020. PMID: 32651390 Free PMC article.
107 results