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Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V.
Quesada-Soriano I, Parker LJ, Primavera A, Wielens J, Holien JK, Casas-Solvas JM, Vargas-Berenguel A, Aguilera AM, Nuccetelli M, Mazzetti AP, Lo Bello M, Parker MW, García-Fuentes L. Quesada-Soriano I, et al. Among authors: lo bello m. J Mol Recognit. 2011 Mar-Apr;24(2):220-34. doi: 10.1002/jmr.1040. J Mol Recognit. 2011. PMID: 20540076
Influence of the H-site residue 108 on human glutathione transferase P1-1 ligand binding: structure-thermodynamic relationships and thermal stability.
Quesada-Soriano I, Parker LJ, Primavera A, Casas-Solvas JM, Vargas-Berenguel A, Barón C, Morton CJ, Mazzetti AP, Lo Bello M, Parker MW, García-Fuentes L. Quesada-Soriano I, et al. Among authors: lo bello m. Protein Sci. 2009 Dec;18(12):2454-70. doi: 10.1002/pro.253. Protein Sci. 2009. PMID: 19780048 Free PMC article.
Rational design of an organometallic glutathione transferase inhibitor.
Ang WH, Parker LJ, De Luca A, Juillerat-Jeanneret L, Morton CJ, Lo Bello M, Parker MW, Dyson PJ. Ang WH, et al. Among authors: lo bello m. Angew Chem Int Ed Engl. 2009;48(21):3854-7. doi: 10.1002/anie.200900185. Angew Chem Int Ed Engl. 2009. PMID: 19396894 Free article.
Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.
Parker LJ, Bocedi A, Ascher DB, Aitken JB, Harris HH, Lo Bello M, Ricci G, Morton CJ, Parker MW. Parker LJ, et al. Among authors: lo bello m. Protein Sci. 2017 Feb;26(2):317-326. doi: 10.1002/pro.3084. Epub 2016 Dec 14. Protein Sci. 2017. PMID: 27863446 Free PMC article.
82 results