Lloyd DB - Search Results

1

Crystal structures of cholesteryl ester transfer protein in complex with inhibitors.

Liu S, Mistry A, Reynolds JM, Lloyd DB, Griffor MC, Perry DA, Ruggeri RB, Clark RW, Qiu X. Liu S, et al. Among authors: lloyd db. J Biol Chem. 2012 Oct 26;287(44):37321-9. doi: 10.1074/jbc.M112.380063. Epub 2012 Sep 7. J Biol Chem. 2012. PMID: 22961980 Free PMC article.

2

Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib.

Lloyd DB, Lira ME, Wood LS, Durham LK, Freeman TB, Preston GM, Qiu X, Sugarman E, Bonnette P, Lanzetti A, Milos PM, Thompson JF. Lloyd DB, et al. J Biol Chem. 2005 Apr 15;280(15):14918-22. doi: 10.1074/jbc.M500523200. Epub 2005 Jan 28. J Biol Chem. 2005. PMID: 15681846 Free article. Clinical Trial.

3

Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules.

Qiu X, Mistry A, Ammirati MJ, Chrunyk BA, Clark RW, Cong Y, Culp JS, Danley DE, Freeman TB, Geoghegan KF, Griffor MC, Hawrylik SJ, Hayward CM, Hensley P, Hoth LR, Karam GA, Lira ME, Lloyd DB, McGrath KM, Stutzman-Engwall KJ, Subashi AK, Subashi TA, Thompson JF, Wang IK, Zhao H, Seddon AP. Qiu X, et al. Among authors: lloyd db. Nat Struct Mol Biol. 2007 Feb;14(2):106-13. doi: 10.1038/nsmb1197. Epub 2007 Jan 21. Nat Struct Mol Biol. 2007. PMID: 17237796

4

Assessment of cholesteryl ester transfer protein inhibitors for interaction with proteins involved in the immune response to infection.

Clark RW, Cunningham D, Cong Y, Subashi TA, Tkalcevic GT, Lloyd DB, Boyd JG, Chrunyk BA, Karam GA, Qiu X, Wang IK, Francone OL. Clark RW, et al. Among authors: lloyd db. J Lipid Res. 2010 May;51(5):967-74. doi: 10.1194/jlr.M002295. Epub 2009 Oct 21. J Lipid Res. 2010. PMID: 19965592 Free PMC article.

5

Novel variants in human and monkey CETP.

Lloyd DB, Reynolds JM, Cronan MT, Williams SP, Lira ME, Wood LS, Knight DR, Thompson JF. Lloyd DB, et al. Biochim Biophys Acta. 2005 Oct 15;1737(1):69-75. doi: 10.1016/j.bbalip.2005.09.007. Epub 2005 Oct 3. Biochim Biophys Acta. 2005. PMID: 16226917

6

Frequency and function of CETP variants among individuals of Asian ancestry.

Thompson JF, Reynolds JM, Williams SP, Wood LS, Paciga SA, Lloyd DB. Thompson JF, et al. Among authors: lloyd db. Atherosclerosis. 2009 Jan;202(1):241-7. doi: 10.1016/j.atherosclerosis.2008.03.013. Epub 2008 Mar 22. Atherosclerosis. 2009. PMID: 18468607

7

Transcriptional modulators affect in vivo protein binding to the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase promoters.

Lloyd DB, Thompson JF. Lloyd DB, et al. J Biol Chem. 1995 Oct 27;270(43):25812-8. doi: 10.1074/jbc.270.43.25812. J Biol Chem. 1995. PMID: 7592765 Free article.

8

Mutation of a protease-sensitive region in firefly luciferase alters light emission properties.

Thompson JF, Geoghegan KF, Lloyd DB, Lanzetti AJ, Magyar RA, Anderson SM, Branchini BR. Thompson JF, et al. Among authors: lloyd db. J Biol Chem. 1997 Jul 25;272(30):18766-71. doi: 10.1074/jbc.272.30.18766. J Biol Chem. 1997. PMID: 9228050 Free article.

9

Cholesteryl ester transfer protein promoter single-nucleotide polymorphisms in Sp1-binding sites affect transcription and are associated with high-density lipoprotein cholesterol.

Thompson JF, Lloyd DB, Lira ME, Milos PM. Thompson JF, et al. Among authors: lloyd db. Clin Genet. 2004 Sep;66(3):223-8. doi: 10.1111/j.1399-0004.2004.00289.x. Clin Genet. 2004. PMID: 15324321

10

Expression of CETP and of splice variants induces the same level of ER stress despite secretion efficiency differences.

Lira ME, Loomis AK, Paciga SA, Lloyd DB, Thompson JF. Lira ME, et al. Among authors: lloyd db. J Lipid Res. 2008 Sep;49(9):1955-62. doi: 10.1194/jlr.M800078-JLR200. Epub 2008 May 28. J Lipid Res. 2008. PMID: 18509195 Free article.

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