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First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma.
Kim RD, Sarker D, Meyer T, Yau T, Macarulla T, Park JW, Choo SP, Hollebecque A, Sung MW, Lim HY, Mazzaferro V, Trojan J, Zhu AX, Yoon JH, Sharma S, Lin ZZ, Chan SL, Faivre S, Feun LG, Yen CJ, Dufour JF, Palmer DH, Llovet JM, Manoogian M, Tugnait M, Stransky N, Hagel M, Kohl NE, Lengauer C, Sherwin CA, Schmidt-Kittler O, Hoeflich KP, Shi H, Wolf BB, Kang YK. Kim RD, et al. Among authors: llovet jm. Cancer Discov. 2019 Dec;9(12):1696-1707. doi: 10.1158/2159-8290.CD-19-0555. Epub 2019 Oct 1. Cancer Discov. 2019. PMID: 31575541 Free article. Clinical Trial.
Diagnosis and treatment of hepatocellular carcinoma.
Suarez Y, Sala M, Llovet JM, Bruix J. Suarez Y, et al. Among authors: llovet jm. Acta Gastroenterol Belg. 1999 Oct-Dec;62(4):410-4. Acta Gastroenterol Belg. 1999. PMID: 10692771 Review.
Hepatocellular carcinoma.
Llovet JM, Burroughs A, Bruix J. Llovet JM, et al. Lancet. 2003 Dec 6;362(9399):1907-17. doi: 10.1016/S0140-6736(03)14964-1. Lancet. 2003. PMID: 14667750 Review.
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation.
Kremer-Tal S, Narla G, Chen Y, Hod E, DiFeo A, Yea S, Lee JS, Schwartz M, Thung SN, Fiel IM, Banck M, Zimran E, Thorgeirsson SS, Mazzaferro V, Bruix J, Martignetti JA, Llovet JM, Friedman SL. Kremer-Tal S, et al. Among authors: llovet jm. J Hepatol. 2007 Apr;46(4):645-54. doi: 10.1016/j.jhep.2006.10.012. Epub 2006 Nov 27. J Hepatol. 2007. PMID: 17196295 Free PMC article.
Genomics and signaling pathways in hepatocellular carcinoma.
Villanueva A, Newell P, Chiang DY, Friedman SL, Llovet JM. Villanueva A, et al. Among authors: llovet jm. Semin Liver Dis. 2007 Feb;27(1):55-76. doi: 10.1055/s-2006-960171. Semin Liver Dis. 2007. PMID: 17295177 Review.
356 results