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The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models.
Masanas M, Masiá N, Suárez-Cabrera L, Olivan M, Soriano A, Majem B, Devis-Jauregui L, Burgos-Panadero R, Jiménez C, Rodriguez-Sodupe P, Boloix A, Toledano I, Guillén G, Navarro A, Llobet-Navas D, Villanueva A, Sánchez de Toledo J, Roma J, Noguera R, Moreno L, Krauss R, Gallego S, Santamaria A, Segura MF. Masanas M, et al. Clin Transl Med. 2021 Oct;11(10):e533. doi: 10.1002/ctm2.533. Clin Transl Med. 2021. PMID: 34709738 Free PMC article. No abstract available.
Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer.
Eritja N, Chen BJ, Rodríguez-Barrueco R, Santacana M, Gatius S, Vidal A, Martí MD, Ponce J, Bergadà L, Yeramian A, Encinas M, Ribera J, Reventós J, Boyd J, Villanueva A, Matias-Guiu X, Dolcet X, Llobet-Navàs D. Eritja N, et al. Autophagy. 2017 Mar 4;13(3):608-624. doi: 10.1080/15548627.2016.1271512. Epub 2017 Jan 5. Autophagy. 2017. PMID: 28055301 Free PMC article.
Autophagy in the physiological endometrium and cancer.
Devis-Jauregui L, Eritja N, Davis ML, Matias-Guiu X, Llobet-Navàs D. Devis-Jauregui L, et al. Autophagy. 2021 May;17(5):1077-1095. doi: 10.1080/15548627.2020.1752548. Epub 2020 May 13. Autophagy. 2021. PMID: 32401642 Free PMC article. Review.
Neuronal Differentiation-Related Epigenetic Regulator ZRF1 Has Independent Prognostic Value in Neuroblastoma but Is Functionally Dispensable In Vitro.
Jiménez C, Antonelli R, Masanas M, Soriano A, Devis-Jauregui L, Camacho J, Magdaleno A, Guillén G, Hladun R, Jubierre L, Roma J, Llobet-Navas D, Sánchez de Toledo J, Moreno L, Gallego S, Segura MF. Jiménez C, et al. Cancers (Basel). 2021 Sep 28;13(19):4845. doi: 10.3390/cancers13194845. Cancers (Basel). 2021. PMID: 34638328 Free PMC article.
A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG.
Rodríguez-Barrueco R, Latorre J, Devis-Jáuregui L, Lluch A, Bonifaci N, Llobet FJ, Olivan M, Coll-Iglesias L, Gassner K, Davis ML, Moreno-Navarrete JM, Castells-Nobau A, Plata-Peña L, Dalmau-Pastor M, Höring M, Liebisch G, Olkkonen VM, Arnoriaga-Rodríguez M, Ricart W, Fernández-Real JM, Silva JM, Ortega FJ, Llobet-Navas D. Rodríguez-Barrueco R, et al. Among authors: llobet navas d. Adv Sci (Weinh). 2022 Feb;9(4):e2104759. doi: 10.1002/advs.202104759. Epub 2021 Dec 13. Adv Sci (Weinh). 2022. PMID: 34898027 Free PMC article.
Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program.
Jiménez C, Antonelli R, Nadal-Ribelles M, Devis-Jauregui L, Latorre P, Solé C, Masanas M, Molero-Valenzuela A, Soriano A, Sánchez de Toledo J, Llobet-Navas D, Roma J, Posas F, de Nadal E, Gallego S, Moreno L, Segura MF. Jiménez C, et al. Among authors: llobet navas d. Mol Cancer. 2022 Sep 3;21(1):175. doi: 10.1186/s12943-022-01643-4. Mol Cancer. 2022. PMID: 36057593 Free PMC article.
Generation and Integrated Analysis of Advanced Patient-Derived Orthoxenograft Models (PDOX) for the Rational Assessment of Targeted Therapies in Endometrial Cancer.
Devis-Jauregui L, Vidal A, Plata-Peña L, Santacana M, García-Mulero S, Bonifaci N, Noguera-Delgado E, Ruiz N, Gil M, Dorca E, Llobet FJ, Coll-Iglesias L, Gassner K, Martinez-Iniesta M, Rodriguez-Barrueco R, Barahona M, Marti L, Viñals F, Ponce J, Sanz-Pamplona R, Piulats JM, Vivancos A, Matias-Guiu X, Villanueva A, Llobet-Navas D. Devis-Jauregui L, et al. Among authors: llobet navas d. Adv Sci (Weinh). 2022 Nov 14;10(1):e2204211. doi: 10.1002/advs.202204211. Online ahead of print. Adv Sci (Weinh). 2022. PMID: 36373729 Free PMC article.
Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers.
Rodriguez-Barrueco R, Yu J, Saucedo-Cuevas LP, Olivan M, Llobet-Navas D, Putcha P, Castro V, Murga-Penas EM, Collazo-Lorduy A, Castillo-Martin M, Alvarez M, Cordon-Cardo C, Kalinsky K, Maurer M, Califano A, Silva JM. Rodriguez-Barrueco R, et al. Genes Dev. 2015 Aug 1;29(15):1631-48. doi: 10.1101/gad.262642.115. Epub 2015 Jul 30. Genes Dev. 2015. PMID: 26227964 Free PMC article.
Oxidative stress-induced FAK activation contributes to uterine serous carcinoma aggressiveness.
Lopez-Mejia IC, Pijuan J, Navaridas R, Santacana M, Gatius S, Velasco A, Castellà G, Panosa A, Cabiscol E, Pinyol M, Coll L, Bonifaci N, Peña LP, Vidal A, Villanueva A, Gari E, Llobet-Navàs D, Fajas L, Matias-Guiu X, Yeramian A. Lopez-Mejia IC, et al. Among authors: llobet navas d. Mol Oncol. 2023 Jan;17(1):98-118. doi: 10.1002/1878-0261.13346. Epub 2022 Dec 7. Mol Oncol. 2023. PMID: 36409196 Free PMC article.
31 results