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TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma.
J Immunother Cancer. 2023 Feb;11(2):e006121. doi: 10.1136/jitc-2022-006121.
J Immunother Cancer. 2023.
PMID: 36808076
Free PMC article.
Treatment of an aggressive orthotopic murine glioblastoma model with combination checkpoint blockade and a multivalent neoantigen vaccine.
Liu CJ, Schaettler M, Blaha DT, Bowman-Kirigin JA, Kobayashi DK, Livingstone AJ, Bender D, Miller CA, Kranz DM, Johanns TM, Dunn GP.
Liu CJ, et al. Among authors: livingstone aj.
Neuro Oncol. 2020 Sep 29;22(9):1276-1288. doi: 10.1093/neuonc/noaa050.
Neuro Oncol. 2020.
PMID: 32133512
Free PMC article.
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The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain.
Bowman-Kirigin JA, Desai R, Saunders BT, Wang AZ, Schaettler MO, Liu CJ, Livingstone AJ, Kobayashi DK, Durai V, Kretzer NM, Zipfel GJ, Leuthardt EC, Osbun JW, Chicoine MR, Kim AH, Murphy KM, Johanns TM, Zinselmeyer BH, Dunn GP.
Bowman-Kirigin JA, et al. Among authors: livingstone aj.
Cancer Immunol Res. 2023 Jan 3;11(1):20-37. doi: 10.1158/2326-6066.CIR-22-0098.
Cancer Immunol Res. 2023.
PMID: 36409838
Free PMC article.
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Impact of CD4 T cells on intratumoral CD8 T-cell exhaustion and responsiveness to PD-1 blockade therapy in mouse brain tumors.
Khan SM, Desai R, Coxon A, Livingstone A, Dunn GP, Petti A, Johanns TM.
Khan SM, et al.
J Immunother Cancer. 2022 Dec;10(12):e005293. doi: 10.1136/jitc-2022-005293.
J Immunother Cancer. 2022.
PMID: 36543376
Free PMC article.
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Glioblastoma-infiltrating CD8+ T cells are predominantly a clonally expanded GZMK+ effector population.
Wang AZ, Mashimo BL, Schaettler MO, Sherpa ND, Leavitt LA, Livingstone AJ, Khan SM, Li M, Anzaldua-Campos MI, Bradley JD, Leuthardt EC, Kim AH, Dowling JL, Chicoine MR, Jones PS, Choi BD, Cahill DP, Carter BS, Petti AA, Johanns TM, Dunn GP.
Wang AZ, et al. Among authors: livingstone aj.
Cancer Discov. 2024 Feb 28. doi: 10.1158/2159-8290.CD-23-0913. Online ahead of print.
Cancer Discov. 2024.
PMID: 38416133
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Integrating multisector molecular characterization into personalized peptide vaccine design for patients with newly diagnosed glioblastoma.
Johanns TM, Garfinkle EAR, Miller KE, Livingstone AJ, Roberts KF, Rao Venkata LP, Dowling JL, Chicoine MR, Dacey RG, Zipfel GJ, Kim AH, Mardis ER, Dunn GP.
Johanns TM, et al. Among authors: livingstone aj.
Clin Cancer Res. 2024 Apr 19. doi: 10.1158/1078-0432.CCR-23-3077. Online ahead of print.
Clin Cancer Res. 2024.
PMID: 38639919
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