Liu Z - Search Results

1

Anionic nanoplastic contaminants promote Parkinson's disease-associated α-synuclein aggregation.

Liu Z, Sokratian A, Duda AM, Xu E, Stanhope C, Fu A, Strader S, Li H, Yuan Y, Bobay BG, Sipe J, Bai K, Lundgaard I, Liu N, Hernandez B, Bowes Rickman C, Miller SE, West AB. Liu Z, et al. Among authors: liu n. Sci Adv. 2023 Nov 15;9(46):eadi8716. doi: 10.1126/sciadv.adi8716. Epub 2023 Nov 17. Sci Adv. 2023. PMID: 37976362 Free PMC article.

2

LRRK2 autophosphorylation enhances its GTPase activity.

Liu Z, Mobley JA, DeLucas LJ, Kahn RA, West AB. Liu Z, et al. FASEB J. 2016 Jan;30(1):336-47. doi: 10.1096/fj.15-277095. Epub 2015 Sep 22. FASEB J. 2016. PMID: 26396237 Free PMC article.

3

G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.

Volpicelli-Daley LA, Abdelmotilib H, Liu Z, Stoyka L, Daher JP, Milnerwood AJ, Unni VK, Hirst WD, Yue Z, Zhao HT, Fraser K, Kennedy RE, West AB. Volpicelli-Daley LA, et al. Among authors: liu z. J Neurosci. 2016 Jul 13;36(28):7415-27. doi: 10.1523/JNEUROSCI.3642-15.2016. J Neurosci. 2016. PMID: 27413152 Free PMC article.

4

The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro.

Liu Z, West AB. Liu Z, et al. Biochim Biophys Acta Proteins Proteom. 2017 Mar;1865(3):274-280. doi: 10.1016/j.bbapap.2016.12.001. Epub 2016 Dec 8. Biochim Biophys Acta Proteins Proteom. 2017. PMID: 27939437 Free PMC article.

5

Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF).

Ivanova AA, Caspary T, Seyfried NT, Duong DM, West AB, Liu Z, Kahn RA. Ivanova AA, et al. Among authors: liu z. J Biol Chem. 2017 Jun 30;292(26):11091-11108. doi: 10.1074/jbc.M117.784025. Epub 2017 May 9. J Biol Chem. 2017. PMID: 28487361 Free PMC article.

6

α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration.

Abdelmotilib H, Maltbie T, Delic V, Liu Z, Hu X, Fraser KB, Moehle MS, Stoyka L, Anabtawi N, Krendelchtchikova V, Volpicelli-Daley LA, West A. Abdelmotilib H, et al. Among authors: liu z. Neurobiol Dis. 2017 Sep;105:84-98. doi: 10.1016/j.nbd.2017.05.014. Epub 2017 May 30. Neurobiol Dis. 2017. PMID: 28576704 Free PMC article.

7

α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration.

Harms AS, Delic V, Thome AD, Bryant N, Liu Z, Chandra S, Jurkuvenaite A, West AB. Harms AS, et al. Among authors: liu z. Acta Neuropathol Commun. 2017 Nov 21;5(1):85. doi: 10.1186/s40478-017-0494-9. Acta Neuropathol Commun. 2017. PMID: 29162163 Free PMC article.

8

Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers.

Wang S, Liu Z, Ye T, Mabrouk OS, Maltbie T, Aasly J, West AB. Wang S, et al. Among authors: liu z. Acta Neuropathol Commun. 2017 Nov 22;5(1):86. doi: 10.1186/s40478-017-0492-y. Acta Neuropathol Commun. 2017. PMID: 29166931 Free PMC article.

9

LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network.

Liu Z, Bryant N, Kumaran R, Beilina A, Abeliovich A, Cookson MR, West AB. Liu Z, et al. Hum Mol Genet. 2018 Jan 15;27(2):385-395. doi: 10.1093/hmg/ddx410. Hum Mol Genet. 2018. PMID: 29177506 Free PMC article.

10

The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition.

Kelly K, Wang S, Boddu R, Liu Z, Moukha-Chafiq O, Augelli-Szafran C, West AB. Kelly K, et al. Among authors: liu z. Exp Neurol. 2018 Nov;309:1-13. doi: 10.1016/j.expneurol.2018.07.012. Epub 2018 Jul 24. Exp Neurol. 2018. PMID: 30048714 Free PMC article.

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