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Modulation of DNA methylation by a sesquiterpene lactone parthenolide.
Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, Wu LC, Rush L, Wang H, Perrotti D, Marcucci G, Chan KK. Liu Z, et al. Among authors: liu s. J Pharmacol Exp Ther. 2009 May;329(2):505-14. doi: 10.1124/jpet.108.147934. Epub 2009 Feb 6. J Pharmacol Exp Ther. 2009. PMID: 19201992 Free PMC article.
Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.
Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G. Liu S, et al. Among authors: liu z. J Pharmacol Exp Ther. 2007 Jun;321(3):953-60. doi: 10.1124/jpet.106.118406. Epub 2007 Mar 26. J Pharmacol Exp Ther. 2007. PMID: 17389244
Curcumin is a potent DNA hypomethylation agent.
Liu Z, Xie Z, Jones W, Pavlovicz RE, Liu S, Yu J, Li PK, Lin J, Fuchs JR, Marcucci G, Li C, Chan KK. Liu Z, et al. Among authors: liu s. Bioorg Med Chem Lett. 2009 Feb 1;19(3):706-9. doi: 10.1016/j.bmcl.2008.12.041. Epub 2008 Dec 14. Bioorg Med Chem Lett. 2009. PMID: 19112019
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B.
Fabbri M, Garzon R, Cimmino A, Liu Z, Zanesi N, Callegari E, Liu S, Alder H, Costinean S, Fernandez-Cymering C, Volinia S, Guler G, Morrison CD, Chan KK, Marcucci G, Calin GA, Huebner K, Croce CM. Fabbri M, et al. Among authors: liu z, liu s. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15805-10. doi: 10.1073/pnas.0707628104. Epub 2007 Sep 21. Proc Natl Acad Sci U S A. 2007. PMID: 17890317 Free PMC article.
Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia.
Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosavljevic T, Takeki M, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, Perrotti D, Caligiuri MA, Chan KK, Wu LC, Marcucci G. Liu S, et al. Among authors: liu z. Blood. 2008 Feb 15;111(4):2364-73. doi: 10.1182/blood-2007-08-110171. Epub 2007 Dec 14. Blood. 2008. PMID: 18083845 Free PMC article.
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, Havelange V, Volinia S, Blum W, Rush LJ, Perrotti D, Andreeff M, Bloomfield CD, Byrd JC, Chan K, Wu LC, Croce CM, Marcucci G. Garzon R, et al. Among authors: liu z, liu s. Blood. 2009 Jun 18;113(25):6411-8. doi: 10.1182/blood-2008-07-170589. Epub 2009 Feb 11. Blood. 2009. PMID: 19211935 Free PMC article.
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