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MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets.
Qiu X, Boufaied N, Hallal T, Feit A, de Polo A, Luoma AM, Alahmadi W, Larocque J, Zadra G, Xie Y, Gu S, Tang Q, Zhang Y, Syamala S, Seo JH, Bell C, O'Connor E, Liu Y, Schaeffer EM, Jeffrey Karnes R, Weinmann S, Davicioni E, Morrissey C, Cejas P, Ellis L, Loda M, Wucherpfennig KW, Pomerantz MM, Spratt DE, Corey E, Freedman ML, Shirley Liu X, Brown M, Long HW, Labbé DP. Qiu X, et al. Among authors: liu y. Nat Commun. 2022 May 13;13(1):2559. doi: 10.1038/s41467-022-30257-z. Nat Commun. 2022. PMID: 35562350 Free PMC article.
Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes.
Weiner AB, Vidotto T, Liu Y, Mendes AA, Salles DC, Faisal FA, Murali S, McFarlane M, Imada EL, Zhao X, Li Z, Davicioni E, Marchionni L, Chinnaiyan AM, Freedland SJ, Spratt DE, Wu JD, Lotan TL, Schaeffer EM. Weiner AB, et al. Among authors: liu y. Nat Commun. 2021 Feb 10;12(1):935. doi: 10.1038/s41467-021-21245-w. Nat Commun. 2021. PMID: 33568675 Free PMC article.
Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence.
Wu Z, Zhou J, Zhang X, Zhang Z, Xie Y, Liu JB, Ho ZV, Panda A, Qiu X, Cejas P, Cañadas I, Akarca FG, McFarland JM, Nagaraja AK, Goss LB, Kesten N, Si L, Lim K, Liu Y, Zhang Y, Baek JY, Liu Y, Patil DT, Katz JP, Hai J, Bao C, Stachler M, Qi J, Ishizuka JJ, Nakagawa H, Rustgi AK, Wong KK, Meyerson M, Barbie DA, Brown M, Long H, Bass AJ. Wu Z, et al. Among authors: liu y, liu jb. Nat Genet. 2021 Jun;53(6):881-894. doi: 10.1038/s41588-021-00859-2. Epub 2021 May 10. Nat Genet. 2021. PMID: 33972779 Free PMC article.
Transcriptomic Heterogeneity of Gleason Grade Group 5 Prostate Cancer.
Kishan AU, Romero T, Alshalalfa M, Liu Y, Tran PT, Nickols NG, Ye H, Sajed D, Rettig MB, Reiter RE, Garraway IP, Spratt DE, Freedland SJ, Zhao X, Li Z, Deek M, Livingstone J, Mahal BA, Nguyen PL, Feng FY, Den RB, Schaeffer EM, Lotan TL, Karnes RJ, Klein EA, Ross AE, Grogan T, Davicioni E, Elashoff D, Boutros PC, Weidhaas JB. Kishan AU, et al. Among authors: liu y. Eur Urol. 2020 Sep;78(3):327-332. doi: 10.1016/j.eururo.2020.05.009. Epub 2020 May 24. Eur Urol. 2020. PMID: 32461072 Free PMC article.
Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences.
Rayford W, Beksac AT, Alger J, Alshalalfa M, Ahmed M, Khan I, Falagario UG, Liu Y, Davicioni E, Spratt DE, Schaeffer EM, Feng FY, Mahal B, Nguyen PL, Den RB, Greenberger MD, Bradley R, Watson JM, Beamer M, Stamatakis L, Carmen DJ, Awasthi S, Hwang J, Weil R, Merisaari H, Mohamed N, Deane LA, Chakravarty D, Yadav KK, Yamoah K, Nair SS, Tewari AK. Rayford W, et al. Among authors: liu y. Commun Biol. 2021 Jun 3;4(1):670. doi: 10.1038/s42003-021-02140-y. Commun Biol. 2021. PMID: 34083737 Free PMC article.
A transcriptomic model for homologous recombination deficiency in prostate cancer.
Weiner AB, Liu Y, McFarlane M, Bawa PS, Li EV, Zhao X, Li Z, Hammoud T, Hazime M, Karnes RJ, Davicioni E, Reichert ZR, Chinnaiyan AM, Lotan TL, Spratt DE, Schaeffer EM. Weiner AB, et al. Among authors: liu y. Prostate Cancer Prostatic Dis. 2022 Apr;25(4):659-665. doi: 10.1038/s41391-021-00416-2. Epub 2021 Jul 5. Prostate Cancer Prostatic Dis. 2022. PMID: 34226663
Novel Transcriptomic Interactions Between Immune Content and Genomic Classifier Predict Lethal Outcomes in High-grade Prostate Cancer.
Yamoah K, Awasthi S, Mahal BA, Zhao SG, Grass GD, Berglund A, Abraham-Miranda J, Gerke T, Rounbehler RJ, Davicioni E, Liu Y, Park J, Cleveland JL, Pow-Sang JM, Fernandez D, Torres-Roca J, Karnes RJ, Schaeffer E, Freedland SJ, Spratt DE, Den RB, Rebbeck TR, Feng F. Yamoah K, et al. Among authors: liu y. Eur Urol. 2022 Apr;81(4):325-330. doi: 10.1016/j.eururo.2020.11.038. Epub 2020 Dec 7. Eur Urol. 2022. PMID: 33303244 Free PMC article.
Prostate-specific Membrane Antigen and Fluciclovine Transporter Genes are Associated with Variable Clinical Features and Molecular Subtypes of Primary Prostate Cancer.
Chu CE, Alshalalfa M, Sjöström M, Zhao SG, Liu Y, Chou J, Herlemann A, Mahal B, Kishan AU, Spratt DE, Cooperberg M, Small E, Wong A, Porten S, Hope TA, Ross AE, Davicioni E, Nguyen P, Karnes RJ, Carroll PR, Schaeffer E, Feng FY. Chu CE, et al. Among authors: liu y. Eur Urol. 2021 Jun;79(6):717-721. doi: 10.1016/j.eururo.2021.03.017. Epub 2021 Apr 8. Eur Urol. 2021. PMID: 33840559
Doublecortin Expression in Prostate Adenocarcinoma and Neuroendocrine Tumors.
Tabrizi S, Alshalalfa M, Mahal BA, Davicioni E, Liu Y, Mouw KW, Feng F, Nguyen PL, Muralidhar V. Tabrizi S, et al. Among authors: liu y. Int J Radiat Oncol Biol Phys. 2020 Nov 15;108(4):936-940. doi: 10.1016/j.ijrobp.2020.06.024. Epub 2020 Jun 22. Int J Radiat Oncol Biol Phys. 2020. PMID: 32585335
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