Liu Y - Search Results

1

Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria.

Taft BR, Yokokawa F, Kirrane T, Mata AC, Huang R, Blaquiere N, Waldron G, Zou B, Simon O, Vankadara S, Chan WL, Ding M, Sim S, Straimer J, Guiguemde A, Lakshminarayana SB, Jain JP, Bodenreider C, Thompson C, Lanshoeft C, Shu W, Fang E, Qumber J, Chan K, Pei L, Chen YL, Schulz H, Lim J, Abas SN, Ang X, Liu Y, Angulo-Barturen I, Jiménez-Díaz MB, Gamo FJ, Crespo-Fernandez B, Rosenthal PJ, Cooper RA, Tumwebaze P, Aguiar ACC, Campo B, Campbell S, Wagner J, Diagana TT, Sarko C. Taft BR, et al. Among authors: liu y. J Med Chem. 2022 Mar 10;65(5):3798-3813. doi: 10.1021/acs.jmedchem.1c01995. Epub 2022 Mar 1. J Med Chem. 2022. PMID: 35229610 Free PMC article.

2

Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis.

Chianelli D, Rucker PV, Roland J, Tully DC, Nelson J, Liu X, Bursulaya B, Hernandez ED, Wu J, Prashad M, Schlama T, Liu Y, Chu A, Schmeits J, Huang DJ, Hill R, Bao D, Zoll J, Kim Y, Groessl T, McNamara P, Liu B, Richmond W, Sancho-Martinez I, Phimister A, Seidel HM, Badman MK, Joseph SB, Laffitte B, Molteni V. Chianelli D, et al. Among authors: liu y, liu x, liu b. J Med Chem. 2020 Apr 23;63(8):3868-3880. doi: 10.1021/acs.jmedchem.9b01621. Epub 2020 Feb 5. J Med Chem. 2020. PMID: 31940200

3

Asymmetric synthesis of α-amino acids by reduction of N-tert-butanesulfinyl ketimine esters.

Reddy LR, Gupta AP, Liu Y. Reddy LR, et al. Among authors: liu y. J Org Chem. 2011 May 6;76(9):3409-15. doi: 10.1021/jo200401a. Epub 2011 Apr 11. J Org Chem. 2011. PMID: 21462993

4

Rhodium-catalyzed asymmetric arylation of N-(tert-butanesulfinyl)imines with sodium tetraarylborates.

Reddy LR, Gupta AP, Villhauer E, Liu Y. Reddy LR, et al. Among authors: liu y. J Org Chem. 2012 Jan 20;77(2):1095-100. doi: 10.1021/jo2024224. Epub 2012 Jan 3. J Org Chem. 2012. PMID: 22185461

5

The First Enantioselective Synthesis of (2R,2'R)-threo-(+)-Methylphenidate Hydrochloride.

Prashad M, Kim HY, Lu Y, Liu Y, Har D, Repic O, Blacklock TJ, Giannousis P. Prashad M, et al. Among authors: liu y. J Org Chem. 1999 Mar 5;64(5):1750-1753. doi: 10.1021/jo9821473. J Org Chem. 1999. PMID: 11674251 No abstract available.

6

Palladium-catalyzed amination of aryl bromides with hindered N-alkyl-substituted anilines using a palladium(I) tri-tert-butylphosphine bromide dimer.

Prashad M, Mak XY, Liu Y, Repic O. Prashad M, et al. Among authors: liu y. J Org Chem. 2003 Feb 7;68(3):1163-4. doi: 10.1021/jo020609d. J Org Chem. 2003. PMID: 12558453

7

A facile asymmetric synthesis of either enantiomer of 2-substituted pyrrolidines.

Rajender Reddy L, Das SG, Liu Y, Prashad M. Rajender Reddy L, et al. Among authors: liu y. J Org Chem. 2010 Apr 2;75(7):2236-46. doi: 10.1021/jo902710s. J Org Chem. 2010. PMID: 20201593

8

Toward the Development of a General Chiral Auxiliary. 5. High Diastereofacial Selectivity in Cycloadditions with Trienol Silyl Ethers: An Application to an Enantioselective Synthesis of (-)-Cassioside.

Boeckman RK Jr, Liu Y. Boeckman RK Jr, et al. Among authors: liu y. J Org Chem. 1996 Nov 15;61(23):7984-7985. doi: 10.1021/jo961613q. J Org Chem. 1996. PMID: 11667770 No abstract available.

9

Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling.

Kwak YS, Kanter AD, Wang B, Liu Y. Kwak YS, et al. Among authors: liu y. Chem Commun (Camb). 2009 Apr 28;(16):2145-7. doi: 10.1039/b902779c. Epub 2009 Mar 23. Chem Commun (Camb). 2009. PMID: 19360174

10

The integrated stress response promotes neural stem cell survival under conditions of mitochondrial dysfunction in neurodegeneration.

Iqbal MA, Bilen M, Liu Y, Jabre V, Fong BC, Chakroun I, Paul S, Chen J, Wade S, Kanaan M, Harper ME, Khacho M, Slack RS. Iqbal MA, et al. Among authors: liu y. Aging Cell. 2024 May 16:e14165. doi: 10.1111/acel.14165. Online ahead of print. Aging Cell. 2024. PMID: 38757355

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