Liu Y - Search Results

1

Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Zhang T, Qu R, Chan S, Lai M, Tong L, Feng F, Chen H, Song T, Song P, Bai G, Liu Y, Wang Y, Li Y, Su Y, Shen Y, Sun Y, Chen Y, Geng M, Ding K, Ding J, Xie H. Zhang T, et al. Among authors: liu y. Mol Cancer. 2020 May 13;19(1):90. doi: 10.1186/s12943-020-01202-9. Mol Cancer. 2020. PMID: 32404161 Free PMC article.

2

Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5- d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors.

Xun Q, Zhang Z, Luo J, Tong L, Huang M, Wang Z, Zou J, Liu Y, Xu Y, Xie H, Tu ZC, Lu X, Ding K. Xun Q, et al. Among authors: liu y. J Med Chem. 2018 Mar 22;61(6):2353-2371. doi: 10.1021/acs.jmedchem.7b01612. Epub 2018 Mar 13. J Med Chem. 2018. PMID: 29499108

3

Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R.

Liu YQ, Wang YN, Lu XY, Tong LJ, Li Y, Zhang T, Xun QJ, Feng F, Chen YZ, Su Y, Shen YY, Chen Y, Geng MY, Ding K, Li YL, Xie H, Ding J. Liu YQ, et al. Acta Pharmacol Sin. 2018 Nov;39(11):1768-1776. doi: 10.1038/s41401-018-0056-0. Epub 2018 Jul 3. Acta Pharmacol Sin. 2018. PMID: 29968849 Free PMC article.

4

Discovery and Biological evaluation of pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors.

Diao Y, Fang X, Song P, Lai M, Tong L, Hao Y, Dou D, Liu Y, Ding J, Zhao Z, Xie H, Li H. Diao Y, et al. Among authors: liu y. Bioorg Med Chem. 2019 Aug 1;27(15):3390-3395. doi: 10.1016/j.bmc.2019.06.023. Epub 2019 Jun 12. Bioorg Med Chem. 2019. PMID: 31221612

5

Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o-Aminopyridyl Alkynyl Scaffold as Potential Treatment for Inflammatory Disorders.

Xie Z, Wu B, Liu Y, Ren W, Tong L, Xiang C, Wei A, Gao Y, Zeng L, Xie H, Tang W, Hu Y. Xie Z, et al. Among authors: liu y. J Med Chem. 2020 Feb 13;63(3):1397-1414. doi: 10.1021/acs.jmedchem.9b01912. Epub 2020 Jan 14. J Med Chem. 2020. PMID: 31934767

6

Correction to: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Zhang T, Qu R, Chan S, Lai M, Tong L, Feng F, Chen H, Song T, Song P, Bai G, Liu Y, Wang Y, Li Y, Su Y, Shen Y, Sun Y, Chen Y, Geng M, Ding K, Ding J, Xie H. Zhang T, et al. Among authors: liu y. Mol Cancer. 2021 Aug 17;20(1):102. doi: 10.1186/s12943-021-01391-x. Mol Cancer. 2021. PMID: 34404402 Free PMC article. No abstract available.

7

LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.

Liu Y, Lai M, Li S, Wang Y, Feng F, Zhang T, Tong L, Zhang M, Chen H, Chen Y, Song P, Li Y, Bai G, Ning Y, Tang H, Fang Y, Chen Y, Lu X, Geng M, Ding K, Yu K, Xie H, Ding J. Liu Y, et al. Cancer Sci. 2022 Feb;113(2):709-720. doi: 10.1111/cas.15229. Epub 2021 Dec 16. Cancer Sci. 2022. PMID: 34855271 Free PMC article.

8

ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK.

Song P, Bai G, Chan S, Zhang T, Tong L, Su Y, Shen Y, Chen Y, Liu Y, Lai M, Ning Y, Tang H, Fang Y, Chen Y, Ding K, Ding J, Xie H. Song P, et al. Among authors: liu y. Front Pharmacol. 2022 Dec 15;13:1071114. doi: 10.3389/fphar.2022.1071114. eCollection 2022. Front Pharmacol. 2022. PMID: 36588692 Free PMC article.

9

Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo.

Lai M, Zhang T, Chen H, Song P, Tong L, Chen J, Liu Y, Ning Y, Feng F, Li Y, Tang H, Chen Y, Fang Y, Lu X, Geng M, Ding K, Yu K, Ding J, Xie H. Lai M, et al. Among authors: liu y. J Cancer. 2023 Jan 1;14(1):152-162. doi: 10.7150/jca.77788. eCollection 2023. J Cancer. 2023. PMID: 36605493 Free PMC article.

10

Correction: Discovery of a novel third-generation EGFR inhibitor and identification of a potential combination strategy to overcome resistance.

Zhang T, Qu R, Chan S, Lai M, Tong L, Feng F, Chen H, Song T, Song P, Bai G, Liu Y, Wang Y, Li Y, Su Y, Shen Y, Sun Y, Chen Y, Geng M, Ding K, Ding J, Xie H. Zhang T, et al. Among authors: liu y. Mol Cancer. 2023 Aug 19;22(1):139. doi: 10.1186/s12943-023-01842-7. Mol Cancer. 2023. PMID: 37598189 Free PMC article. No abstract available.

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