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Plasmodium kinesin-8X associates with mitotic spindles and is essential for oocyst development during parasite proliferation and transmission.
Zeeshan M, Shilliday F, Liu T, Abel S, Mourier T, Ferguson DJP, Rea E, Stanway RR, Roques M, Williams D, Daniel E, Brady D, Roberts AJ, Holder AA, Pain A, Le Roch KG, Moores CA, Tewari R. Zeeshan M, et al. Among authors: liu t. PLoS Pathog. 2019 Oct 10;15(10):e1008048. doi: 10.1371/journal.ppat.1008048. eCollection 2019 Oct. PLoS Pathog. 2019. PMID: 31600347 Free PMC article.
Taxanes convert regions of perturbed microtubule growth into rescue sites.
Rai A, Liu T, Glauser S, Katrukha EA, Estévez-Gallego J, Rodríguez-García R, Fang WS, Díaz JF, Steinmetz MO, Altmann KH, Kapitein LC, Moores CA, Akhmanova A. Rai A, et al. Among authors: liu t. Nat Mater. 2020 Mar;19(3):355-365. doi: 10.1038/s41563-019-0546-6. Epub 2019 Dec 9. Nat Mater. 2020. PMID: 31819210
Inhibiting parasite proliferation using a rationally designed anti-tubulin agent.
Gaillard N, Sharma A, Abbaali I, Liu T, Shilliday F, Cook AD, Ehrhard V, Bangera M, Roberts AJ, Moores CA, Morrissette N, Steinmetz MO. Gaillard N, et al. Among authors: liu t. EMBO Mol Med. 2021 Nov 8;13(11):e13818. doi: 10.15252/emmm.202013818. Epub 2021 Oct 18. EMBO Mol Med. 2021. PMID: 34661376 Free PMC article.
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