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Short-chain diamines are the physiological substrates of PACE family efflux pumps.
Hassan KA, Naidu V, Edgerton JR, Mettrick KA, Liu Q, Fahmy L, Li L, Jackson SM, Ahmad I, Sharples D, Henderson PJF, Paulsen IT. Hassan KA, et al. Among authors: liu q. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):18015-18020. doi: 10.1073/pnas.1901591116. Epub 2019 Aug 15. Proc Natl Acad Sci U S A. 2019. PMID: 31416917 Free PMC article.
Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens.
Hassan KA, Liu Q, Elbourne LDH, Ahmad I, Sharples D, Naidu V, Chan CL, Li L, Harborne SPD, Pokhrel A, Postis VLG, Goldman A, Henderson PJF, Paulsen IT. Hassan KA, et al. Among authors: liu q. Res Microbiol. 2018 Sep-Oct;169(7-8):450-454. doi: 10.1016/j.resmic.2018.01.001. Epub 2018 Feb 2. Res Microbiol. 2018. PMID: 29409983 Free PMC article. Review.
An ace up their sleeve: a transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens.
Hassan KA, Elbourne LD, Li L, Gamage HK, Liu Q, Jackson SM, Sharples D, Kolstø AB, Henderson PJ, Paulsen IT. Hassan KA, et al. Among authors: liu q. Front Microbiol. 2015 Apr 22;6:333. doi: 10.3389/fmicb.2015.00333. eCollection 2015. Front Microbiol. 2015. PMID: 25954261 Free PMC article.
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