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A basophil-neuronal axis promotes itch.
Wang F, Trier AM, Li F, Kim S, Chen Z, Chai JN, Mack MR, Morrison SA, Hamilton JD, Baek J, Yang TB, Ver Heul AM, Xu AZ, Xie Z, Dong X, Kubo M, Hu H, Hsieh CS, Dong X, Liu Q, Margolis DJ, Ardeleanu M, Miller MJ, Kim BS. Wang F, et al. Among authors: liu q. Cell. 2021 Jan 21;184(2):422-440.e17. doi: 10.1016/j.cell.2020.12.033. Epub 2021 Jan 14. Cell. 2021. PMID: 33450207 Free PMC article.
Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch.
Oetjen LK, Mack MR, Feng J, Whelan TM, Niu H, Guo CJ, Chen S, Trier AM, Xu AZ, Tripathi SV, Luo J, Gao X, Yang L, Hamilton SL, Wang PL, Brestoff JR, Council ML, Brasington R, Schaffer A, Brombacher F, Hsieh CS, Gereau RW 4th, Miller MJ, Chen ZF, Hu H, Davidson S, Liu Q, Kim BS. Oetjen LK, et al. Among authors: liu q. Cell. 2017 Sep 21;171(1):217-228.e13. doi: 10.1016/j.cell.2017.08.006. Epub 2017 Sep 7. Cell. 2017. PMID: 28890086 Free PMC article.
IL-33 signaling in sensory neurons promotes dry skin itch.
Trier AM, Mack MR, Fredman A, Tamari M, Ver Heul AM, Zhao Y, Guo CJ, Avraham O, Ford ZK, Oetjen LK, Feng J, Dehner C, Coble D, Badic A, Joshita S, Kubo M, Gereau RW 4th, Alexander-Brett J, Cavalli V, Davidson S, Hu H, Liu Q, Kim BS. Trier AM, et al. Among authors: liu q. J Allergy Clin Immunol. 2022 Apr;149(4):1473-1480.e6. doi: 10.1016/j.jaci.2021.09.014. Epub 2021 Sep 21. J Allergy Clin Immunol. 2022. PMID: 34560104 Free PMC article.
The role of the Mrgpr receptor family in itch.
Liu Q, Dong X. Liu Q, et al. Handb Exp Pharmacol. 2015;226:71-88. doi: 10.1007/978-3-662-44605-8_5. Handb Exp Pharmacol. 2015. PMID: 25861775 Review.
A histamine-independent itch pathway is required for allergic ocular itch.
Huang CC, Kim YS, Olson WP, Li F, Guo C, Luo W, Huang AJW, Liu Q. Huang CC, et al. Among authors: liu q. J Allergy Clin Immunol. 2016 Apr;137(4):1267-1270.e6. doi: 10.1016/j.jaci.2015.08.047. Epub 2015 Oct 28. J Allergy Clin Immunol. 2016. PMID: 26521042 Free PMC article.
Transient receptor potential vanilloid 4-expressing macrophages and keratinocytes contribute differentially to allergic and nonallergic chronic itch.
Luo J, Feng J, Yu G, Yang P, Mack MR, Du J, Yu W, Qian A, Zhang Y, Liu S, Yin S, Xu A, Cheng J, Liu Q, O'Neil RG, Xia Y, Ma L, Carlton SM, Kim BS, Renner K, Liu Q, Hu H. Luo J, et al. Among authors: liu s, liu q. J Allergy Clin Immunol. 2018 Feb;141(2):608-619.e7. doi: 10.1016/j.jaci.2017.05.051. Epub 2017 Aug 11. J Allergy Clin Immunol. 2018. PMID: 28807414 Free PMC article.
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