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Graft-infiltrating host dendritic cells play a key role in organ transplant rejection.
Zhuang Q, Liu Q, Divito SJ, Zeng Q, Yatim KM, Hughes AD, Rojas-Canales DM, Nakao A, Shufesky WJ, Williams AL, Humar R, Hoffman RA, Shlomchik WD, Oberbarnscheidt MH, Lakkis FG, Morelli AE. Zhuang Q, et al. Among authors: liu q. Nat Commun. 2016 Aug 24;7:12623. doi: 10.1038/ncomms12623. Nat Commun. 2016. PMID: 27554168 Free PMC article.
Graft IL-33 regulates infiltrating macrophages to protect against chronic rejection.
Li T, Zhang Z, Bartolacci JG, Dwyer GK, Liu Q, Mathews LR, Velayutham M, Roessing AS, Lee YC, Dai H, Shiva S, Oberbarnscheidt MH, Dziki JL, Mullet SJ, Wendell SG, Wilkinson JD, Webber SA, Wood-Trageser M, Watkins SC, Demetris AJ, Hussey GS, Badylak SF, Turnquist HR. Li T, et al. Among authors: liu q. J Clin Invest. 2020 Oct 1;130(10):5397-5412. doi: 10.1172/JCI133008. J Clin Invest. 2020. PMID: 32644975 Free PMC article.
IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival.
Turnquist HR, Zhao Z, Rosborough BR, Liu Q, Castellaneta A, Isse K, Wang Z, Lang M, Stolz DB, Zheng XX, Demetris AJ, Liew FY, Wood KJ, Thomson AW. Turnquist HR, et al. Among authors: liu q. J Immunol. 2011 Nov 1;187(9):4598-610. doi: 10.4049/jimmunol.1100519. Epub 2011 Sep 26. J Immunol. 2011. PMID: 21949025 Free PMC article.
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