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Chutes and ladders in hepatitis C nucleoside drug development.
Coats SJ, Garnier-Amblard EC, Amblard F, Ehteshami M, Amiralaei S, Zhang H, Zhou L, Boucle SR, Lu X, Bondada L, Shelton JR, Li H, Liu P, Li C, Cho JH, Chavre SN, Zhou S, Mathew J, Schinazi RF. Coats SJ, et al. Among authors: liu p. Antiviral Res. 2014 Feb;102:119-47. doi: 10.1016/j.antiviral.2013.11.008. Epub 2013 Nov 23. Antiviral Res. 2014. PMID: 24275341 Free PMC article. Review.
Synthesis and biological evaluation of new potent and selective HCV NS5A inhibitors.
Shi J, Zhou L, Amblard F, Bobeck DR, Zhang H, Liu P, Bondada L, McBrayer TR, Tharnish PM, Whitaker T, Coats SJ, Schinazi RF. Shi J, et al. Among authors: liu p. Bioorg Med Chem Lett. 2012 May 15;22(10):3488-91. doi: 10.1016/j.bmcl.2012.03.089. Epub 2012 Mar 29. Bioorg Med Chem Lett. 2012. PMID: 22507961 Free PMC article.
Azetidines and spiro azetidines as novel P2 units in hepatitis C virus NS3 protease inhibitors.
Bondada L, Rondla R, Pradere U, Liu P, Li C, Bobeck D, McBrayer T, Tharnish P, Courcambeck J, Halfon P, Whitaker T, Amblard F, Coats SJ, Schinazi RF. Bondada L, et al. Among authors: liu p. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6325-30. doi: 10.1016/j.bmcl.2013.09.068. Epub 2013 Sep 30. Bioorg Med Chem Lett. 2013. PMID: 24135727 Free PMC article.
Substrates and Inhibitors of SAMHD1.
Hollenbaugh JA, Shelton J, Tao S, Amiralaei S, Liu P, Lu X, Goetze RW, Zhou L, Nettles JH, Schinazi RF, Kim B. Hollenbaugh JA, et al. Among authors: liu p. PLoS One. 2017 Jan 3;12(1):e0169052. doi: 10.1371/journal.pone.0169052. eCollection 2017. PLoS One. 2017. PMID: 28046007 Free PMC article.
2'-Chloro,2'-fluoro Ribonucleotide Prodrugs with Potent Pan-genotypic Activity against Hepatitis C Virus Replication in Culture.
Zhou S, Mahmoud S, Liu P, Zhou L, Ehteshami M, Bassit L, Tao S, Domaoal RA, Sari O, Schutter C, Amiralaei S, Khalil A, Ollinger Russell O, McBrayer T, Whitaker T, Abou-Taleb N, Amblard F, Coats SJ, Schinazi RF. Zhou S, et al. Among authors: liu p. J Med Chem. 2017 Jul 13;60(13):5424-5437. doi: 10.1021/acs.jmedchem.7b00067. Epub 2017 Jun 26. J Med Chem. 2017. PMID: 28595015
Structural and Antiviral Studies of the Human Norovirus GII.4 Protease.
Muzzarelli KM, Kuiper B, Spellmon N, Brunzelle J, Hackett J, Amblard F, Zhou S, Liu P, Kovari IA, Yang Z, Schinazi RF, Kovari LC. Muzzarelli KM, et al. Among authors: liu p. Biochemistry. 2019 Feb 19;58(7):900-907. doi: 10.1021/acs.biochem.8b01063. Epub 2019 Jan 16. Biochemistry. 2019. PMID: 30605321 Free PMC article.
Comparison of anti-SARS-CoV-2 activity and intracellular metabolism of remdesivir and its parent nucleoside.
Tao S, Zandi K, Bassit L, Ong YT, Verma K, Liu P, Downs-Bowen JA, McBrayer T, LeCher JC, Kohler JJ, Tedbury PR, Kim B, Amblard F, Sarafianos SG, Schinazi RF. Tao S, et al. Among authors: liu p. Curr Res Pharmacol Drug Discov. 2021;2:100045. doi: 10.1016/j.crphar.2021.100045. Epub 2021 Aug 12. Curr Res Pharmacol Drug Discov. 2021. PMID: 34870151 Free PMC article.
Synthesis and evaluation of highly potent HBV capsid assembly modulators (CAMs).
Amblard F, Chen Z, Wiseman J, Zhou S, Liu P, Salman M, Verma K, Azadi N, Downs-Bowen J, Tao S, Kumari A, Zhang Q, Smith DB, Patel D, Bassit L, Schinazi RF. Amblard F, et al. Among authors: liu p. Bioorg Chem. 2023 Dec;141:106923. doi: 10.1016/j.bioorg.2023.106923. Epub 2023 Oct 20. Bioorg Chem. 2023. PMID: 37871391
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