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Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD.
Sun H, Deng T, Zhang Y, Lin Y, Jiang Y, Jiang Y, Huang Y, Song S, Cui L, Li T, Xiong H, Lan M, Liu L, Li Y, Fang Q, Yu K, Jiang W, Zhou L, Que Y, Zhang T, Yuan Q, Cheng T, Zhang Z, Yu H, Zhang J, Luo W, Li S, Zheng Q, Gu Y, Xia N. Sun H, et al. Among authors: liu l. Protein Cell. 2024 Feb 1;15(2):121-134. doi: 10.1093/procel/pwad040. Protein Cell. 2024. PMID: 37470320 Free PMC article.
A Bacterially Expressed SARS-CoV-2 Receptor Binding Domain Fused With Cross-Reacting Material 197 A-Domain Elicits High Level of Neutralizing Antibodies in Mice.
Liu L, Chen T, Zhou L, Sun J, Li Y, Nie M, Xiong H, Zhu Y, Xue W, Wu Y, Li T, Zhang T, Kong Z, Yu H, Zhang J, Gu Y, Zheng Q, Zhao Q, Xia N, Li S. Liu L, et al. Front Microbiol. 2022 Apr 26;13:854630. doi: 10.3389/fmicb.2022.854630. eCollection 2022. Front Microbiol. 2022. PMID: 35558112 Free PMC article.
Three SARS-CoV-2 antibodies provide broad and synergistic neutralization against variants of concern, including Omicron.
Wang S, Sun H, Zhang Y, Yuan L, Wang Y, Zhang T, Wang S, Zhang J, Yu H, Xiong H, Tang Z, Liu L, Huang Y, Chen X, Li T, Ying D, Liu C, Chen Z, Yuan Q, Zhang J, Cheng T, Li S, Guan Y, Zheng Q, Zheng Z, Xia N. Wang S, et al. Among authors: liu l, liu c. Cell Rep. 2022 May 24;39(8):110862. doi: 10.1016/j.celrep.2022.110862. Epub 2022 May 8. Cell Rep. 2022. PMID: 35594869 Free PMC article.
The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2.
Xiong H, Sun H, Wang S, Yuan L, Liu L, Zhu Y, Zhang J, Huang Y, Qi R, Jiang Y, Ma J, Zhou M, Ma Y, Fu R, Yan S, Yue M, Wu Y, Wei M, Wang Y, Li T, Wang Y, Zheng Z, Yu H, Cheng T, Li S, Yuan Q, Zhang J, Guan Y, Zheng Q, Zhang T, Xia N. Xiong H, et al. Among authors: liu l. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2204256119. doi: 10.1073/pnas.2204256119. Epub 2022 Aug 16. Proc Natl Acad Sci U S A. 2022. PMID: 35972965 Free PMC article.
Structural basis for the synergistic neutralization of coxsackievirus B1 by a triple-antibody cocktail.
Zheng Q, Zhu R, Yin Z, Xu L, Sun H, Yu H, Wu Y, Jiang Y, Huang Q, Huang Y, Zhang D, Liu L, Yang H, He M, Zhou Z, Jiang Y, Chen Z, Zhao H, Que Y, Kong Z, Zhou L, Li T, Zhang J, Luo W, Gu Y, Cheng T, Li S, Xia N. Zheng Q, et al. Among authors: liu l. Cell Host Microbe. 2022 Sep 14;30(9):1279-1294.e6. doi: 10.1016/j.chom.2022.08.001. Epub 2022 Aug 23. Cell Host Microbe. 2022. PMID: 36002016 Free article.
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