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Biological Characterization of a Stable Effector Functionless (SEFL) Monoclonal Antibody Scaffold in Vitro.
Liu L, Jacobsen FW, Everds N, Zhuang Y, Yu YB, Li N, Clark D, Nguyen MP, Fort M, Narayanan P, Kim K, Stevenson R, Narhi L, Gunasekaran K, Bussiere JL. Liu L, et al. J Biol Chem. 2017 Feb 3;292(5):1876-1883. doi: 10.1074/jbc.M116.748707. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994063 Free PMC article.
The engineering and stability and pharmacokinetic assessments of the SEFL scaffold is described in the accompanying article (Jacobsen, F. W., Stevenson, R., Li, C., Salimi-Moosavi, H., Liu, L., Wen, J., Luo, Q., Daris, K., Buck, L., Miller, S., Ho, S-Y., Wang …
The engineering and stability and pharmacokinetic assessments of the SEFL scaffold is described in the accompanying article (Jacobsen, F. W. …
Engineering an IgG Scaffold Lacking Effector Function with Optimized Developability.
Jacobsen FW, Stevenson R, Li C, Salimi-Moosavi H, Liu L, Wen J, Luo Q, Daris K, Buck L, Miller S, Ho SY, Wang W, Chen Q, Walker K, Wypych J, Narhi L, Gunasekaran K. Jacobsen FW, et al. Among authors: liu l. J Biol Chem. 2017 Feb 3;292(5):1865-1875. doi: 10.1074/jbc.M116.748525. Epub 2016 Dec 19. J Biol Chem. 2017. PMID: 27994062 Free PMC article.
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair.
Florio M, Gunasekaran K, Stolina M, Li X, Liu L, Tipton B, Salimi-Moosavi H, Asuncion FJ, Li C, Sun B, Tan HL, Zhang L, Han CY, Case R, Duguay AN, Grisanti M, Stevens J, Pretorius JK, Pacheco E, Jones H, Chen Q, Soriano BD, Wen J, Heron B, Jacobsen FW, Brisan E, Richards WG, Ke HZ, Ominsky MS. Florio M, et al. Among authors: liu l. Nat Commun. 2016 May 27;7:11505. doi: 10.1038/ncomms11505. Nat Commun. 2016. PMID: 27230681 Free PMC article.
NSUN2 mediates distinct pathways to regulate enterovirus 71 replication.
Liu L, Chen Z, Zhang K, Hao H, Ma L, Liu H, Yu B, Ding S, Zhang X, Zhu M, Guo X, Liu Y, Liu H, Huang F, Peng K, Guan W. Liu L, et al. Virol Sin. 2024 May 18:S1995-820X(24)00070-1. doi: 10.1016/j.virs.2024.05.002. Online ahead of print. Virol Sin. 2024. PMID: 38768712
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