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Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity.
Poulet B, Liu K, Plumb D, Vo P, Shah M, Staines K, Sampson A, Nakamura H, Nagase H, Carriero A, Shefelbine S, Pitsillides AA, Bou-Gharios G. Poulet B, et al. Among authors: liu k. PLoS One. 2016 Dec 21;11(12):e0167971. doi: 10.1371/journal.pone.0167971. eCollection 2016. PLoS One. 2016. PMID: 28002442 Free PMC article.
Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria.
Hughes JH, Liu K, Plagge A, Wilson PJM, Sutherland H, Norman BP, Hughes AT, Keenan CM, Milan AM, Sakai T, Ranganath LR, Gallagher JA, Bou-Gharios G. Hughes JH, et al. Among authors: liu k. Hum Mol Genet. 2019 Dec 1;28(23):3928-3939. doi: 10.1093/hmg/ddz234. Hum Mol Genet. 2019. PMID: 31600782 Free PMC article.
Venous identity requires BMP signalling through ALK3.
Neal A, Nornes S, Payne S, Wallace MD, Fritzsche M, Louphrasitthiphol P, Wilkinson RN, Chouliaras KM, Liu K, Plant K, Sholapurkar R, Ratnayaka I, Herzog W, Bond G, Chico T, Bou-Gharios G, De Val S. Neal A, et al. Among authors: liu k. Nat Commun. 2019 Jan 28;10(1):453. doi: 10.1038/s41467-019-08315-w. Nat Commun. 2019. PMID: 30692543 Free PMC article.
Syndecan-3 enhances anabolic bone formation through WNT signaling.
Johnson de Sousa Brito FM, Butcher A, Pisconti A, Poulet B, Prior A, Charlesworth G, Sperinck C, Scotto di Mase M, Liu K, Bou-Gharios G, Jurgen van 't Hof R, Daroszewska A. Johnson de Sousa Brito FM, et al. Among authors: liu k. FASEB J. 2021 Apr;35(4):e21246. doi: 10.1096/fj.202002024R. FASEB J. 2021. PMID: 33769615 Free PMC article.
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