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211 results

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PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, Liu JO, Dawson TM, Dawson VL. Park H, et al. Among authors: liu jo. Cell. 2022 May 26;185(11):1943-1959.e21. doi: 10.1016/j.cell.2022.04.020. Epub 2022 May 10. Cell. 2022. PMID: 35545089 Free PMC article.
Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa.
Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, Sharrock AV, Brandon C, Park H, Kam TI, Dawson VL, Dawson TM, Shim JS, Hanes J, Ji H, Liu JO, Qian J, Ackerley DF, Rohrer B, Zack DJ, Mumm JS. Zhang L, et al. Among authors: liu jo. Elife. 2021 Jun 29;10:e57245. doi: 10.7554/eLife.57245. Elife. 2021. PMID: 34184634 Free PMC article.
Discovery of a Potent GLUT Inhibitor from a Library of Rapafucins by Using 3D Microarrays.
Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao AVS, Li RJ, Ying X, Korangath P, Liberti MV, Li Y, Xie Y, Hong SY, Schiene-Fischer C, Fischer G, Locasale JW, Sukumar S, Zhu H, Liu JO. Guo Z, et al. Among authors: liu jo, liu w. Angew Chem Int Ed Engl. 2019 Nov 25;58(48):17158-17162. doi: 10.1002/anie.201905578. Epub 2019 Oct 31. Angew Chem Int Ed Engl. 2019. PMID: 31591797 Free PMC article.
Rapamycin-inspired macrocycles with new target specificity.
Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, Coe I, Paavilainen VO, Sun Z, Liu JO. Guo Z, et al. Among authors: liu jo, liu w. Nat Chem. 2019 Mar;11(3):254-263. doi: 10.1038/s41557-018-0187-4. Epub 2018 Dec 10. Nat Chem. 2019. PMID: 30532015 Free PMC article.
Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes.
Cui Z, Liu Y, Wan W, Xu Y, Hu Y, Ding M, Dou X, Wang R, Li H, Meng Y, Li W, Jiang W, Li Z, Li Y, Tan M, Ma DK, Ding Y, Liu JO, Luo C, Yu B, Tang Q, Dang Y. Cui Z, et al. Among authors: liu y, liu jo. Protein Cell. 2021 Jun;12(6):493-501. doi: 10.1007/s13238-020-00717-7. Protein Cell. 2021. PMID: 32399897 Free PMC article. No abstract available.
211 results