Liu JG - Search Results

1

Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors.

Li C, Hu SS, Yang L, Wang M, Long JD, Wang B, Han H, Zhu H, Zhao S, Liu JG, Liu D, Liu H. Li C, et al. Among authors: liu h, liu jg, liu d. ACS Med Chem Lett. 2021 Mar 1;12(3):397-403. doi: 10.1021/acsmedchemlett.0c00559. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738067 Free PMC article.

2

Formation of aversive memories associated with conditioned drug withdrawal requires BDNF expression in the amygdala in acute morphine-dependent rats.

Ju YY, Long JD, Liu Y, Liu JG. Ju YY, et al. Among authors: liu y, liu jg. Acta Pharmacol Sin. 2015 Dec;36(12):1437-43. doi: 10.1038/aps.2015.94. Epub 2015 Nov 16. Acta Pharmacol Sin. 2015. PMID: 26567727 Free PMC article.

3

Discovery of Potent and Selective Agonists of δ Opioid Receptor by Revisiting the "Message-Address" Concept.

Shen Q, Qian Y, Huang X, Xu X, Li W, Liu J, Fu W. Shen Q, et al. ACS Med Chem Lett. 2016 Feb 10;7(4):391-6. doi: 10.1021/acsmedchemlett.5b00423. eCollection 2016 Apr 14. ACS Med Chem Lett. 2016. PMID: 27096047 Free PMC article.

4

The Pharmacological Heterogeneity of Nepenthone Analogs in Conferring Highly Selective and Potent κ-Opioid Agonistic Activities.

Li W, Long JD, Qian YY, Long Y, Xu XJ, Wang YJ, Shen Q, Wang ZN, Yang XC, Xiao L, Sun HP, Xu YL, Chen YY, Xie Q, Wang YH, Shao LM, Liu JG, Qiu ZB, Fu W. Li W, et al. Among authors: liu jg. ACS Chem Neurosci. 2017 Apr 19;8(4):766-776. doi: 10.1021/acschemneuro.6b00321. Epub 2017 Jan 19. ACS Chem Neurosci. 2017. PMID: 28033462

5

The neuroprotective effect of memantine on methamphetamine-induced cognitive deficits.

Long JD, Liu Y, Jiao DL, Wang YJ, Zan GY, Ju YY, Zhao M, Liu JG. Long JD, et al. Among authors: liu y, liu jg. Behav Brain Res. 2017 Apr 14;323:133-140. doi: 10.1016/j.bbr.2017.01.042. Epub 2017 Jan 29. Behav Brain Res. 2017. PMID: 28147236

6

SYVN1, an ERAD E3 Ubiquitin Ligase, Is Involved in GABA_Aα1 Degradation Associated with Methamphetamine-Induced Conditioned Place Preference.

Jiao DL, Chen Y, Liu Y, Ju YY, Long JD, Du J, Yu CX, Wang YJ, Zhao M, Liu JG. Jiao DL, et al. Among authors: liu y, liu jg. Front Mol Neurosci. 2017 Oct 5;10:313. doi: 10.3389/fnmol.2017.00313. eCollection 2017. Front Mol Neurosci. 2017. PMID: 29051727 Free PMC article.

7

Discovery of a Highly Selective and Potent κ Opioid Receptor Agonist from N-Cyclopropylmethyl-7α-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept.

Xiao L, Wang Y, Zhang M, Wu W, Kong L, Ma Y, Xu X, Liu X, He Q, Qian Y, Sun H, Wu H, Lin C, Huang H, Ye R, Jiang S, Ye RF, Yuan C, Fang S, Xue D, Yang X, Chen H, Zheng Y, Yu L, Xie Q, Zheng L, Fu W, Li W, Qiu Z, Liu J, Shao L. Xiao L, et al. J Med Chem. 2019 Dec 26;62(24):11054-11070. doi: 10.1021/acs.jmedchem.9b00857. Epub 2019 Dec 6. J Med Chem. 2019. PMID: 31738550

8

Alteration of twinfilin1 expression underlies opioid withdrawal-induced remodeling of actin cytoskeleton at synapses and formation of aversive memory.

Wang YJ, Yu C, Wu WW, Ju YY, Liu Y, Xu C, Long JD, Zan GY, Wei XY, Zhang LS, Chai JR, Chen Z, Liu JG. Wang YJ, et al. Among authors: liu y, liu jg. Mol Psychiatry. 2021 Nov;26(11):6218-6236. doi: 10.1038/s41380-021-01111-3. Epub 2021 May 7. Mol Psychiatry. 2021. PMID: 33963280

9

Discovery, Structure-Activity Relationship, and Mechanistic Studies of 1-((3R,4S)-3-((Dimethylamino)methyl)-4-hydroxy-4-(3-methoxyphenyl)piperidin-1-yl)-2-(2,4,5-trifluorophenyl)ethan-1-one as a Novel Potent Analgesic.

Huang H, Li X, Xie P, Li X, Xu X, Qian Y, Yuan C, Meng X, Chai J, Chen J, Liu J, Wang W, Li W, Wang Y, Fu W, Liu J. Huang H, et al. J Med Chem. 2021 Jul 8;64(13):9458-9483. doi: 10.1021/acs.jmedchem.1c00722. Epub 2021 Jun 21. J Med Chem. 2021. PMID: 34152138

10

Discovery of an M-Substituted N-Cyclopropylmethyl-7α-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active κ-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile.

He Q, Wei Y, Liu X, Ye R, Kong L, Li Z, Jiang S, Yu L, Chai J, Xie Q, Fu W, Wang Y, Li W, Qiu Z, Liu J, Shao L. He Q, et al. J Med Chem. 2021 Aug 26;64(16):12414-12433. doi: 10.1021/acs.jmedchem.1c01082. Epub 2021 Aug 13. J Med Chem. 2021. PMID: 34387468

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