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USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice.
Dang F, Bai L, Dong J, Hu X, Wang J, Paulo JA, Xiong Y, Liang X, Sun Y, Chen Y, Guo M, Wang X, Huang Z, Inuzuka H, Chen L, Chu C, Liu J, Zhang T, Rezaeian AH, Liu J, Kaniskan HÜ, Zhong B, Zhang J, Letko M, Jin J, Lan K, Wei W. Dang F, et al. Among authors: liu j. Sci Transl Med. 2023 Dec 6;15(725):eadh7668. doi: 10.1126/scitranslmed.adh7668. Epub 2023 Dec 6. Sci Transl Med. 2023. PMID: 38055802
A Potent, Selective, and Cell-Active Inhibitor of Human Type I Protein Arginine Methyltransferases.
Eram MS, Shen Y, Szewczyk M, Wu H, Senisterra G, Li F, Butler KV, Kaniskan HÜ, Speed BA, Dela Seña C, Dong A, Zeng H, Schapira M, Brown PJ, Arrowsmith CH, Barsyte-Lovejoy D, Liu J, Vedadi M, Jin J. Eram MS, et al. Among authors: liu j. ACS Chem Biol. 2016 Mar 18;11(3):772-781. doi: 10.1021/acschembio.5b00839. Epub 2015 Dec 8. ACS Chem Biol. 2016. PMID: 26598975 Free PMC article.
Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.
Shen Y, Szewczyk MM, Eram MS, Smil D, Kaniskan HÜ, de Freitas RF, Senisterra G, Li F, Schapira M, Brown PJ, Arrowsmith CH, Barsyte-Lovejoy D, Liu J, Vedadi M, Jin J. Shen Y, et al. Among authors: liu j. J Med Chem. 2016 Oct 13;59(19):9124-9139. doi: 10.1021/acs.jmedchem.6b01033. Epub 2016 Sep 15. J Med Chem. 2016. PMID: 27584694 Free PMC article.
The APC/C E3 Ligase Complex Activator FZR1 Restricts BRAF Oncogenic Function.
Wan L, Chen M, Cao J, Dai X, Yin Q, Zhang J, Song SJ, Lu Y, Liu J, Inuzuka H, Katon JM, Berry K, Fung J, Ng C, Liu P, Song MS, Xue L, Bronson RT, Kirschner MW, Cui R, Pandolfi PP, Wei W. Wan L, et al. Among authors: liu j, liu p. Cancer Discov. 2017 Apr;7(4):424-441. doi: 10.1158/2159-8290.CD-16-0647. Epub 2017 Feb 7. Cancer Discov. 2017. PMID: 28174173 Free PMC article.
"FEM1"nism controls SLBP stability during cell cycle.
Zhang J, Liu J, Wei W. Zhang J, et al. Among authors: liu j. Cell Cycle. 2017 Apr 3;16(7):597-598. doi: 10.1080/15384101.2017.1302226. Cell Cycle. 2017. PMID: 28324668 Free PMC article. No abstract available.
Degrading proteins in animals: "PROTAC"tion goes in vivo.
Guo J, Liu J, Wei W. Guo J, et al. Among authors: liu j. Cell Res. 2019 Mar;29(3):179-180. doi: 10.1038/s41422-019-0144-9. Cell Res. 2019. PMID: 30770868 Free PMC article. No abstract available.
Targeting SCF E3 Ligases for Cancer Therapies.
Liu J, Peng Y, Zhang J, Long J, Liu J, Wei W. Liu J, et al. Adv Exp Med Biol. 2020;1217:123-146. doi: 10.1007/978-981-15-1025-0_9. Adv Exp Med Biol. 2020. PMID: 31898226 Review.
PROTACs: A novel strategy for cancer therapy.
Liu J, Ma J, Liu Y, Xia J, Li Y, Wang ZP, Wei W. Liu J, et al. Among authors: liu y. Semin Cancer Biol. 2020 Dec;67(Pt 2):171-179. doi: 10.1016/j.semcancer.2020.02.006. Epub 2020 Feb 11. Semin Cancer Biol. 2020. PMID: 32058059 Review.
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