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REGgamma modulates p53 activity by regulating its cellular localization.
Liu J, Yu G, Zhao Y, Zhao D, Wang Y, Wang L, Liu J, Li L, Zeng Y, Dang Y, Wang C, Gao G, Long W, Lonard DM, Qiao S, Tsai MJ, Zhang B, Luo H, Li X. Liu J, et al. J Cell Sci. 2010 Dec 1;123(Pt 23):4076-84. doi: 10.1242/jcs.067405. J Cell Sci. 2010. PMID: 21084564 Free PMC article.
REGγ deficiency promotes premature aging via the casein kinase 1 pathway.
Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Zuo D, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X. Li L, et al. Among authors: liu j. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11005-10. doi: 10.1073/pnas.1308497110. Epub 2013 Jun 13. Proc Natl Acad Sci U S A. 2013. PMID: 23766372 Free PMC article.
The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.
Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. Dong S, et al. Among authors: liu j. Cell Metab. 2013 Sep 3;18(3):380-91. doi: 10.1016/j.cmet.2013.08.012. Cell Metab. 2013. PMID: 24011073 Free PMC article.
PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis.
Liu S, Lai L, Zuo Q, Dai F, Wu L, Wang Y, Zhou Q, Liu J, Liu J, Li L, Lin Q, Creighton CJ, Costello MG, Huang S, Jia C, Liao L, Luo H, Fu J, Liu M, Yi Z, Xiao J, Li X. Liu S, et al. Among authors: liu j, liu m. J Mol Cell Cardiol. 2014 Jul;72:28-38. doi: 10.1016/j.yjmcc.2014.02.007. Epub 2014 Feb 20. J Mol Cell Cardiol. 2014. PMID: 24560667 Free PMC article.
REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway.
Li L, Dang Y, Zhang J, Yan W, Zhai W, Chen H, Li K, Tong L, Gao X, Amjad A, Ji L, Jing T, Jiang Z, Shi K, Yao L, Song D, Liu T, Yang X, Yang C, Cai X, Xu W, Huang Q, He J, Liu J, Chen T, Moses RE, Fu J, Xiao J, Li X. Li L, et al. Among authors: liu j, liu t. Nat Commun. 2015 Apr 24;6:6875. doi: 10.1038/ncomms7875. Nat Commun. 2015. PMID: 25908095 Free article.
REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway.
Chen H, Gao X, Sun Z, Wang Q, Zuo D, Pan L, Li K, Chen J, Chen G, Hu K, Li K, Shah AS, Huang T, Muhammad Zeeshan B, Tong L, Jiao C, Liu J, Chen T, Yao L, Dang Y, Liu T, Li L. Chen H, et al. Among authors: liu j, liu t. Exp Dermatol. 2017 Nov;26(11):1118-1124. doi: 10.1111/exd.13394. Epub 2017 Aug 30. Exp Dermatol. 2017. PMID: 28605165
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