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Glutamatergic synaptic input to glioma cells drives brain tumour progression.
Venkataramani V, Tanev DI, Strahle C, Studier-Fischer A, Fankhauser L, Kessler T, Körber C, Kardorff M, Ratliff M, Xie R, Horstmann H, Messer M, Paik SP, Knabbe J, Sahm F, Kurz FT, Acikgöz AA, Herrmannsdörfer F, Agarwal A, Bergles DE, Chalmers A, Miletic H, Turcan S, Mawrin C, Hänggi D, Liu HK, Wick W, Winkler F, Kuner T. Venkataramani V, et al. Among authors: liu hk. Nature. 2019 Sep;573(7775):532-538. doi: 10.1038/s41586-019-1564-x. Epub 2019 Sep 18. Nature. 2019. PMID: 31534219
Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival.
Zhu Z, Khan MA, Weiler M, Blaes J, Jestaedt L, Geibert M, Zou P, Gronych J, Bernhardt O, Korshunov A, Bugner V, Lichter P, Radlwimmer B, Heiland S, Bendszus M, Wick W, Liu HK. Zhu Z, et al. Among authors: liu hk. Cell Stem Cell. 2014 Aug 7;15(2):185-98. doi: 10.1016/j.stem.2014.04.007. Epub 2014 May 15. Cell Stem Cell. 2014. PMID: 24835569 Free article.
Brain tumour cells interconnect to a functional and resistant network.
Osswald M, Jung E, Sahm F, Solecki G, Venkataramani V, Blaes J, Weil S, Horstmann H, Wiestler B, Syed M, Huang L, Ratliff M, Karimian Jazi K, Kurz FT, Schmenger T, Lemke D, Gömmel M, Pauli M, Liao Y, Häring P, Pusch S, Herl V, Steinhäuser C, Krunic D, Jarahian M, Miletic H, Berghoff AS, Griesbeck O, Kalamakis G, Garaschuk O, Preusser M, Weiss S, Liu H, Heiland S, Platten M, Huber PE, Kuner T, von Deimling A, Wick W, Winkler F. Osswald M, et al. Nature. 2015 Dec 3;528(7580):93-8. doi: 10.1038/nature16071. Epub 2015 Nov 4. Nature. 2015. PMID: 26536111
Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.
Feng W, Kawauchi D, Körkel-Qu H, Deng H, Serger E, Sieber L, Lieberman JA, Jimeno-González S, Lambo S, Hanna BS, Harim Y, Jansen M, Neuerburg A, Friesen O, Zuckermann M, Rajendran V, Gronych J, Ayrault O, Korshunov A, Jones DT, Kool M, Northcott PA, Lichter P, Cortés-Ledesma F, Pfister SM, Liu HK. Feng W, et al. Among authors: liu hk. Nat Commun. 2017 Mar 20;8:14758. doi: 10.1038/ncomms14758. Nat Commun. 2017. PMID: 28317875 Free PMC article.
GPD1 Specifically Marks Dormant Glioma Stem Cells with a Distinct Metabolic Profile.
Rusu P, Shao C, Neuerburg A, Acikgöz AA, Wu Y, Zou P, Phapale P, Shankar TS, Döring K, Dettling S, Körkel-Qu H, Bekki G, Costa B, Guo T, Friesen O, Schlotter M, Heikenwalder M, Tschaharganeh DF, Bukau B, Kramer G, Angel P, Herold-Mende C, Radlwimmer B, Liu HK. Rusu P, et al. Among authors: liu hk. Cell Stem Cell. 2019 Aug 1;25(2):241-257.e8. doi: 10.1016/j.stem.2019.06.004. Epub 2019 Jul 11. Cell Stem Cell. 2019. PMID: 31303549 Free article.
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis.
Pajtler KW, Wei Y, Okonechnikov K, Silva PBG, Vouri M, Zhang L, Brabetz S, Sieber L, Gulley M, Mauermann M, Wedig T, Mack N, Imamura Kawasawa Y, Sharma T, Zuckermann M, Andreiuolo F, Holland E, Maass K, Körkel-Qu H, Liu HK, Sahm F, Capper D, Bunt J, Richards LJ, Jones DTW, Korshunov A, Chavez L, Lichter P, Hoshino M, Pfister SM, Kool M, Li W, Kawauchi D. Pajtler KW, et al. Among authors: liu hk. Nat Commun. 2019 Sep 2;10(1):3914. doi: 10.1038/s41467-019-11884-5. Nat Commun. 2019. PMID: 31477715 Free PMC article.
Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype.
Wu Y, Fletcher M, Gu Z, Wang Q, Costa B, Bertoni A, Man KH, Schlotter M, Felsberg J, Mangei J, Barbus M, Gaupel AC, Wang W, Weiss T, Eils R, Weller M, Liu H, Reifenberger G, Korshunov A, Angel P, Lichter P, Herrmann C, Radlwimmer B. Wu Y, et al. Nat Commun. 2020 Dec 18;11(1):6434. doi: 10.1038/s41467-020-20225-w. Nat Commun. 2020. PMID: 33339831 Free PMC article.
485 results