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Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation.
Zhang T, Xu D, Liu J, Wang M, Duan LJ, Liu M, Meng H, Zhuang Y, Wang H, Wang Y, Lv M, Zhang Z, Hu J, Shi L, Guo R, Xie X, Liu H, Erickson E, Wang Y, Yu W, Dang F, Guan D, Jiang C, Dai X, Inuzuka H, Yan P, Wang J, Babuta M, Lian G, Tu Z, Miao J, Szabo G, Fong GH, Karnoub AE, Lee YR, Pan L, Kaelin WG Jr, Yuan J, Wei W. Zhang T, et al. Among authors: liu j, liu h, liu m. Nat Cell Biol. 2023 Jul;25(7):950-962. doi: 10.1038/s41556-023-01170-4. Epub 2023 Jul 3. Nat Cell Biol. 2023. PMID: 37400498 Free PMC article.
INPP4B Is a PtdIns(3,4,5)P3 Phosphatase That Can Act as a Tumor Suppressor.
Kofuji S, Kimura H, Nakanishi H, Nanjo H, Takasuga S, Liu H, Eguchi S, Nakamura R, Itoh R, Ueno N, Asanuma K, Huang M, Koizumi A, Habuchi T, Yamazaki M, Suzuki A, Sasaki J, Sasaki T. Kofuji S, et al. Among authors: liu h. Cancer Discov. 2015 Jul;5(7):730-9. doi: 10.1158/2159-8290.CD-14-1329. Epub 2015 Apr 16. Cancer Discov. 2015. PMID: 25883023
Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients.
Emerling BM, Benes CH, Poulogiannis G, Bell EL, Courtney K, Liu H, Choo-Wing R, Bellinger G, Tsukazawa KS, Brown V, Signoretti S, Soltoff SP, Cantley LC. Emerling BM, et al. Among authors: liu h. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3483-8. doi: 10.1073/pnas.1222435110. Epub 2013 Feb 1. Proc Natl Acad Sci U S A. 2013. PMID: 23378636 Free PMC article.
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