Liu CC - Search Results

1

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer's disease patient iPSC-derived cerebral organoids.

Zhao J, Fu Y, Yamazaki Y, Ren Y, Davis MD, Liu CC, Lu W, Wang X, Chen K, Cherukuri Y, Jia L, Martens YA, Job L, Shue F, Nguyen TT, Younkin SG, Graff-Radford NR, Wszolek ZK, Brafman DA, Asmann YW, Ertekin-Taner N, Kanekiyo T, Bu G. Zhao J, et al. Among authors: liu cc. Nat Commun. 2020 Nov 2;11(1):5540. doi: 10.1038/s41467-020-19264-0. Nat Commun. 2020. PMID: 33139712 Free PMC article.

2

Heparan sulphate proteoglycan and the low-density lipoprotein receptor-related protein 1 constitute major pathways for neuronal amyloid-beta uptake.

Kanekiyo T, Zhang J, Liu Q, Liu CC, Zhang L, Bu G. Kanekiyo T, et al. Among authors: liu cc, liu q. J Neurosci. 2011 Feb 2;31(5):1644-51. doi: 10.1523/JNEUROSCI.5491-10.2011. J Neurosci. 2011. PMID: 21289173 Free PMC article.

3

LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.

Kanekiyo T, Liu CC, Shinohara M, Li J, Bu G. Kanekiyo T, et al. Among authors: liu cc. J Neurosci. 2012 Nov 14;32(46):16458-65. doi: 10.1523/JNEUROSCI.3987-12.2012. J Neurosci. 2012. PMID: 23152628 Free PMC article.

4

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy.

Liu CC, Liu CC, Kanekiyo T, Xu H, Bu G. Liu CC, et al. Nat Rev Neurol. 2013 Feb;9(2):106-18. doi: 10.1038/nrneurol.2012.263. Epub 2013 Jan 8. Nat Rev Neurol. 2013. PMID: 23296339 Free PMC article. Review.

5

Neuronal clearance of amyloid-β by endocytic receptor LRP1.

Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Kanekiyo T, et al. Among authors: liu cc. J Neurosci. 2013 Dec 4;33(49):19276-83. doi: 10.1523/JNEUROSCI.3487-13.2013. J Neurosci. 2013. PMID: 24305823 Free PMC article.

6

Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway.

Zhao J, Fu Y, Liu CC, Shinohara M, Nielsen HM, Dong Q, Kanekiyo T, Bu G. Zhao J, et al. Among authors: liu cc. J Biol Chem. 2014 Apr 18;289(16):11282-11292. doi: 10.1074/jbc.M113.526095. Epub 2014 Mar 5. J Biol Chem. 2014. PMID: 24599963 Free PMC article.

7

Tyrosine-based signal mediates LRP6 receptor endocytosis and desensitization of Wnt/β-catenin pathway signaling.

Liu CC, Kanekiyo T, Roth B, Bu G. Liu CC, et al. J Biol Chem. 2014 Oct 3;289(40):27562-70. doi: 10.1074/jbc.M113.533927. Epub 2014 Aug 20. J Biol Chem. 2014. PMID: 25143377 Free PMC article.

8

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.

Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Liu CC, et al. Neuron. 2014 Oct 1;84(1):63-77. doi: 10.1016/j.neuron.2014.08.048. Epub 2014 Sep 18. Neuron. 2014. PMID: 25242217 Free PMC article.

9

Neuronal LRP1 regulates glucose metabolism and insulin signaling in the brain.

Liu CC, Hu J, Tsai CW, Yue M, Melrose HL, Kanekiyo T, Bu G. Liu CC, et al. J Neurosci. 2015 Apr 8;35(14):5851-9. doi: 10.1523/JNEUROSCI.5180-14.2015. J Neurosci. 2015. PMID: 25855193 Free PMC article.

10

Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.

Hu J, Liu CC, Chen XF, Zhang YW, Xu H, Bu G. Hu J, et al. Among authors: liu cc. Mol Neurodegener. 2015 Mar 5;10:6. doi: 10.1186/s13024-015-0001-3. Mol Neurodegener. 2015. PMID: 25871773 Free PMC article.

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