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Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation.
Zhou E, Ge X, Nakashima H, Li R, van der Zande HJP, Liu C, Li Z, Müller C, Bracher F, Mohammed Y, de Boer JF, Kuipers F, Guigas B, Glass CK, Rensen PCN, Giera M, Wang Y. Zhou E, et al. Among authors: liu c. EMBO Mol Med. 2023 Aug 7;15(8):e16845. doi: 10.15252/emmm.202216845. Epub 2023 Jun 26. EMBO Mol Med. 2023. PMID: 37357756 Free PMC article.
Hepatic Scavenger Receptor Class B Type 1 Knockdown Reduces Atherosclerosis and Enhances the Antiatherosclerotic Effect of Brown Fat Activation in APOE*3-Leiden.CETP Mice.
Zhou E, Li Z, Nakashima H, Liu C, Ying Z, Foks AC, Berbée JFP, van Dijk KW, Rensen PCN, Wang Y. Zhou E, et al. Among authors: liu c. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1474-1486. doi: 10.1161/ATVBAHA.121.315882. Epub 2021 Feb 11. Arterioscler Thromb Vasc Biol. 2021. PMID: 33567866
FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis.
Liu C, Schönke M, Spoorenberg B, Lambooij JM, van der Zande HJP, Zhou E, Tushuizen ME, Andreasson AC, Park A, Oldham S, Uhrbom M, Ahlstedt I, Ikeda Y, Wallenius K, Peng XR, Guigas B, Boon MR, Wang Y, Rensen PCN. Liu C, et al. Elife. 2023 Jan 17;12:e83075. doi: 10.7554/eLife.83075. Elife. 2023. PMID: 36648330 Free PMC article.
Dietary butyrate ameliorates metabolic health associated with selective proliferation of gut Lachnospiraceae bacterium 28-4.
Li Z, Zhou E, Liu C, Wicks H, Yildiz S, Razack F, Ying Z, Kooijman S, Koonen DPY, Heijink M, Kostidis S, Giera M, Sanders IMJG, Kuijper EJ, Smits WK, van Dijk KW, Rensen PCN, Wang Y. Li Z, et al. Among authors: liu c. JCI Insight. 2023 Feb 22;8(4):e166655. doi: 10.1172/jci.insight.166655. JCI Insight. 2023. PMID: 36810253 Free PMC article.
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