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SALL4B, not targeted by IMiD, is important for SALL4-mediated tumorigenesis.
L Vu KA, Kumari K, Liu BH, Gao C, Li F, Tang JP, Maddalo D, Auld DS, Casalena DE, Tian X, Liu M, Bassal MA, Moein S, Iakovleva V, Tan JL, Stein AJ, Zhou Q, Fischer PD, Sigua LH, Qi J, Arthanari H, Tenen DG, Chai L. L Vu KA, et al. Among authors: liu bh, liu m. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.548071. doi: 10.1101/2023.07.07.548071. bioRxiv. 2023. PMID: 37461690 Free PMC article. Preprint.
A SALL4/MLL/HOXA9 pathway in murine and human myeloid leukemogenesis.
Li A, Yang Y, Gao C, Lu J, Jeong HW, Liu BH, Tang P, Yao X, Neuberg D, Huang G, Tenen DG, Chai L. Li A, et al. Among authors: liu bh. J Clin Invest. 2013 Oct;123(10):4195-207. doi: 10.1172/JCI62891. Epub 2013 Sep 24. J Clin Invest. 2013. PMID: 24051379 Free PMC article.
Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Liu BH, Jobichen C, Chia CSB, Chan THM, Tang JP, Chung TXY, Li J, Poulsen A, Hung AW, Koh-Stenta X, Tan YS, Verma CS, Tan HK, Wu CS, Li F, Hill J, Joy J, Yang H, Chai L, Sivaraman J, Tenen DG. Liu BH, et al. Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7119-E7128. doi: 10.1073/pnas.1801253115. Epub 2018 Jul 5. Proc Natl Acad Sci U S A. 2018. PMID: 29976840 Free PMC article.
New High-Throughput Screening Identifies Compounds That Reduce Viability Specifically in Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation.
Tan JL, Li F, Yeo JZ, Yong KJ, Bassal MA, Ng GH, Lee MY, Leong CY, Tan HK, Wu CS, Liu BH, Chan TH, Tan ZH, Chan YS, Wang S, Lim ZH, Toh TB, Hooi L, Low KN, Ma S, Kong NR, Stein AJ, Wu Y, Thangavelu MT, Suzuki A, Periyasamy G, Asara JM, Dan YY, Bonney GK, Chow EK, Lu GD, Ng HH, Kanagasundaram Y, Ng SB, Tam WL, Tenen DG, Chai L. Tan JL, et al. Among authors: liu bh. Gastroenterology. 2019 Dec;157(6):1615-1629.e17. doi: 10.1053/j.gastro.2019.08.022. Epub 2019 Aug 22. Gastroenterology. 2019. PMID: 31446059 Free PMC article.
Targeting transcription factors through an IMiD independent zinc finger domain.
Liu BH, Liu M, Radhakrishnan S, Jaladanki CK, Gao C, Tang JP, Kumari K, Go ML, Vu KAL, Seo HS, Song K, Tian X, Feng L, Tan JL, Bassal MA, Arthanari H, Qi J, Dhe-Paganon S, Fan H, Tenen DG, Chai L. Liu BH, et al. bioRxiv [Preprint]. 2024 Jan 3:2024.01.03.574032. doi: 10.1101/2024.01.03.574032. bioRxiv. 2024. PMID: 38260640 Free PMC article. Preprint.
455 results