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Page 1
Magnesium sensing via LFA-1 regulates CD8+ T cell effector function.
Lötscher J, Martí I Líndez AA, Kirchhammer N, Cribioli E, Giordano Attianese GMP, Trefny MP, Lenz M, Rothschild SI, Strati P, Künzli M, Lotter C, Schenk SH, Dehio P, Löliger J, Litzler L, Schreiner D, Koch V, Page N, Lee D, Grählert J, Kuzmin D, Burgener AV, Merkler D, Pless M, Balmer ML, Reith W, Huwyler J, Irving M, King CG, Zippelius A, Hess C. Lötscher J, et al. Among authors: litzler l. Cell. 2022 Feb 17;185(4):585-602.e29. doi: 10.1016/j.cell.2021.12.039. Epub 2022 Jan 19. Cell. 2022. PMID: 35051368 Free article.
T resident helper cells promote humoral responses in the lung.
Swarnalekha N, Schreiner D, Litzler LC, Iftikhar S, Kirchmeier D, Künzli M, Son YM, Sun J, Moreira EA, King CG. Swarnalekha N, et al. Among authors: litzler lc. Sci Immunol. 2021 Jan 8;6(55):eabb6808. doi: 10.1126/sciimmunol.abb6808. Sci Immunol. 2021. PMID: 33419790 Free PMC article.
PRMT5 is essential for B cell development and germinal center dynamics.
Litzler LC, Zahn A, Meli AP, Hébert S, Patenaude AM, Methot SP, Sprumont A, Bois T, Kitamura D, Costantino S, King IL, Kleinman CL, Richard S, Di Noia JM. Litzler LC, et al. Nat Commun. 2019 Jan 3;10(1):22. doi: 10.1038/s41467-018-07884-6. Nat Commun. 2019. PMID: 30604754 Free PMC article.
A licensing step links AID to transcription elongation for mutagenesis in B cells.
Methot SP, Litzler LC, Subramani PG, Eranki AK, Fifield H, Patenaude AM, Gilmore JC, Santiago GE, Bagci H, Côté JF, Larijani M, Verdun RE, Di Noia JM. Methot SP, et al. Among authors: litzler lc. Nat Commun. 2018 Mar 28;9(1):1248. doi: 10.1038/s41467-018-03387-6. Nat Commun. 2018. PMID: 29593215 Free PMC article.
HSP90 inhibitors decrease AID levels and activity in mice and in human cells.
Montamat-Sicotte D, Litzler LC, Abreu C, Safavi S, Zahn A, Orthwein A, Müschen M, Oppezzo P, Muñoz DP, Di Noia JM. Montamat-Sicotte D, et al. Among authors: litzler lc. Eur J Immunol. 2015 Aug;45(8):2365-76. doi: 10.1002/eji.201545462. Epub 2015 May 18. Eur J Immunol. 2015. PMID: 25912253 Free PMC article.