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Considerations for Developing Targeted Therapies in Low-Frequency Molecular Subsets of a Disease.
Schuck RN, Woodcock J, Zineh I, Stein P, Jarow J, Temple R, Permutt T, LaVange L, Beaver JA, Charlab R, Blumenthal GM, Dorff SE, Leptak C, Lemery S, Rogers H, Chowdhury B, Litwack ED, Pacanowski M. Schuck RN, et al. Among authors: litwack ed. Clin Pharmacol Ther. 2018 Aug;104(2):282-289. doi: 10.1002/cpt.1041. Epub 2018 Feb 23. Clin Pharmacol Ther. 2018. PMID: 29473145 Free PMC article. Review.
Weighing the Evidence: Variant Classification and Interpretation in Precision Oncology, US Food and Drug Administration Public Workshop-Workshop Proceedings.
Horne HN, Roscoe D, Litwack ED, Pathak A, Pandey JP, Gallagher PS, Koontz LM, Schuck RN, Lee EY, Hu YF, Beaver JA, Blumenthal GM, Philip R. Horne HN, et al. Among authors: litwack ed. JCO Precis Oncol. 2019 Mar 19;3:PO.18.00314. doi: 10.1200/PO.18.00314. eCollection 2019. JCO Precis Oncol. 2019. PMID: 32914013 Free PMC article.
Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development.
Vicini P, Fields O, Lai E, Litwack ED, Martin AM, Morgan TM, Pacanowski MA, Papaluca M, Perez OD, Ringel MS, Robson M, Sakul H, Vockley J, Zaks T, Dolsten M, Søgaard M. Vicini P, et al. Among authors: litwack ed. Clin Pharmacol Ther. 2016 Feb;99(2):198-207. doi: 10.1002/cpt.293. Epub 2015 Dec 19. Clin Pharmacol Ther. 2016. PMID: 26536838 Review.
The FDA and genetic testing.
Litwack ED, Mansfield E, Shuren J. Litwack ED, et al. N Engl J Med. 2015 Jun 4;372(23):2273-4. doi: 10.1056/NEJMc1504604. Epub 2015 May 27. N Engl J Med. 2015. PMID: 26014594 Free article. No abstract available.
24 results