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Increasing the bulk of the 1TEL-target linker and retaining the 10×His tag in a 1TEL-CMG2-vWa construct improves crystal order and diffraction limits.
Gajjar PL, Pedroza Romo MJ, Litchfield CM, Callahan M, Redd N, Nawarathnage S, Soleimani S, Averett J, Wilson E, Lewis A, Stewart C, Tseng YJ, Doukov T, Lebedev A, Moody JD. Gajjar PL, et al. Among authors: litchfield cm. Acta Crystallogr D Struct Biol. 2023 Oct 1;79(Pt 10):925-943. doi: 10.1107/S2059798323007246. Epub 2023 Sep 25. Acta Crystallogr D Struct Biol. 2023. PMID: 37747038 Free PMC article.
Decreasing the flexibility of the TELSAM-target protein linker and omitting the cleavable fusion tag improves crystal order and diffraction limits.
Gajjar PL, Romo MJP, Litchfield CM, Callahan M, Redd N, Nawarathnage S, Soleimani S, Averett J, Wilson E, Lewis A, Stewart C, Tseng YJ, Doukov T, Lebedev A, Moody JD. Gajjar PL, et al. Among authors: litchfield cm. bioRxiv [Preprint]. 2023 May 15:2023.05.12.540586. doi: 10.1101/2023.05.12.540586. bioRxiv. 2023. PMID: 37293010 Free PMC article. Preprint.
Modelling aggressive prostate cancers of young men in immune-competent mice, driven by isogenic Trp53 alterations and Pten loss.
Mejía-Hernández JO, Keam SP, Saleh R, Muntz F, Fox SB, Byrne D, Kogan A, Pang L, Huynh J, Litchfield C, Caramia F, Lozano G, He H, You JM, Sandhu S, Williams SG, Haupt Y, Haupt S. Mejía-Hernández JO, et al. Among authors: litchfield c. Cell Death Dis. 2022 Sep 8;13(9):777. doi: 10.1038/s41419-022-05211-y. Cell Death Dis. 2022. PMID: 36075907 Free PMC article.
Lung Inflammation Is Associated with Preeclampsia Development in the Rat.
Curtis K, Clarke D, Hanegan M, Stapley B, Wendt R, Beckett N, Litchfield C, Campbell K, Reynolds P, Arroyo J. Curtis K, et al. Among authors: litchfield c. Cells. 2022 Jun 10;11(12):1884. doi: 10.3390/cells11121884. Cells. 2022. PMID: 35741013 Free PMC article.
Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.
Zivanovic Bujak A, Weng CF, Silva MJ, Yeung M, Lo L, Ftouni S, Litchfield C, Ko YA, Kuykhoven K, Van Geelen C, Chandrashekar S, Dawson MA, Loi S, Wong SQ, Dawson SJ. Zivanovic Bujak A, et al. Among authors: litchfield c. PLoS Med. 2020 Oct 1;17(10):e1003363. doi: 10.1371/journal.pmed.1003363. eCollection 2020 Oct. PLoS Med. 2020. PMID: 33001984 Free PMC article.
78 results